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MetabolomicsA Combined Proteomic and Metabolomic Strategy for Allergens Characterization in Natural and Fermented Brassica napus Bee Pollen

Bee pollen is consumed for its nutritional and pharmacological benefits, but it also contains hazardous allergens which has not been identified. Here, we identified 2 potential allergens, glutaredoxin and oleosin-B2, in Brassica napus (B. napus) bee pollen using mass spectrometr...

2022-03-23 | MTBLS3950 | MetaboLights
ProteomicsProtein profiling of human serum against a panel of allergens.
Current diagnostics for allergies, such as skin prick and radioallergosorbent tests, do not allow for inexpensive, high-throughput screening of patients. Additionally, extracts used in these methods are made from washed pollen that lacks pollen surface materials that may contain allergens. We soug...
ORGANISM(S): Homo sapiens 
2010-09-08 | E-MTAB-177 | biostudies-arrayexpress
ProteomicsEffects of contact allergens on THP-1 cells – LFQ- and SILAC-based untargeted proteomics
In this study, the effects of the contact allergens BQ, DNCB, NBB, Ni, and PPD were investigated in THP-1 cells. For this purpose, LFQ- and SILAC-based untargeted proteomics were applied.
ORGANISM(S): Homo sapiens (Human) 
2023-09-13 | PXD031017 | Pride
Silac Lfq Thp-1 Contact allergens 
TranscriptomicsTranscription profiling by array of mouse BALBc strain mesenteric lymph nodes after response to common allergens.
In this study, MLN transcriptome profiling of female BALB/c mice was conducted in order to explore the molecular mechanism(s) of antigen sensitization using three of the most common food allergens; BLG, OVA and PNA. Analysis of cDNA microarray data revealed a complex network of genes that is modulat...
ORGANISM(S): Mus musculus 
2011-05-11 | E-MEXP-2676 | biostudies-arrayexpress
ProteomicsMass spectrometry analysis of cleavage sites for different protease allergens in human IL-33
The cytokine interleukin-33 (IL-33) is an epithelial alarmin with critical roles in allergic inflammation and type 2 immunity. The project aims at the characterization of the direct cleavage of IL-33 by allergen proteases, resulting in its activation, and in the subsequent induction of type 2 cytoki...
ORGANISM(S): Homo sapiens (Human) Oryctolagus cuniculus (Rabbit) 
2018-03-14 | PXD006081 | Pride
Peptide mapping Interleukin-33 Human Protease processing Lc-ms/ms 
GenomicsIdentification of allergens in pitaya seeds
Identify allergens in white-fleshed and red-fleshed pitaya seeds
PRJEB57868 | ENA
ProteomicsQualitative PTM characterization of raw and roasted peanut allergens from aqueous extracts by HRMS
Project is related to immunoproteomic profiling of soluble fractions of raw and roasted peanut. It is still unknown which peanut extract is more allergenic, the raw or roasted version and part of the answer could be in revealing differences between PTM profiles of the raw and roasted peanut.
ORGANISM(S): Arachis hypogaea (Peanut) 
2023-03-11 | PXD033166 | Pride
Roasting Modifications Peanut Allergens Ptm profiling 
ProteomicsComparative seed proteome profile reveals no alternation of major allergens of high yielding mung bean cultivars
Mung bean contains up to 25% of the protein, is one of the great sources of plant-based protein. Since many allergens also function as defense-related proteins, it is important to determine their abundance level in the high-yielding disease-resistant cultivars. In this study, for the first time, we ...
ORGANISM(S): Vigna Radiata (ncbitaxon:157791) 
2024-01-19 | MSV000093895 | MassIVE
GenomicsA developing HPA axis permits neonatal immune sensitivity to common allergens
A developing HPA axis permits neonatal immune sensitivity to common allergens
PRJNA1140218 | ENA
GenomicsA developing HPA axis permits neonatal immune sensitivity to common allergens.
A developing HPA axis permits neonatal immune sensitivity to common allergens.
PRJNA1277576 | ENA
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