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ProteomicsAtherosclerotic environment effect over CAC pre-angiogenic role
In response to vascular injury, early EPC or Circulating angiogenic cells (CAC) are thought to be recruited to the damaged areas, participating mainly in a paracrine fashion, by releasing pro-angiogenic factors, promoting the mobilization of other cell populations such as the late EPC, or endothelia...
ORGANISM(S): Homo sapiens (Human) 
2021-09-09 | PXD019395 | Pride
Proteomics Angiogenesis Circulating angiogenic cells Atherosclerotic factors Paracrine role Endothelial colony forming cells Secretome 
ProteomicsLong-term changes following pre-conditioned circulating angiogenic cells therapy in critical limb ischemia
Critical limb ischemia (CLI), results from a severe blockade of the arterial vessels, is usually correlated to atherosclerosis. Circulating angiogenic cells (CACs) constitute a good alternative as CLI cell therapy due to their vascular regenerative potential, although the mechanisms of action of the...
ORGANISM(S): Mus musculus (Mouse) 
2022-02-16 | PXD024132 | Pride
Neovascularization Circulating angiogenic cells Immune cells Atherosclerotic secretome Critical limb ischemia 
ProteomicsTHE ATHEROMA PLAQUE SECRETOME STIMULATES THE MOBILIZATION OF ENDOTHELIAL PROGENITOR CELLS EX VIVO
in this study we evaluated the initial response promoted by the atherosclerotic plaque (AP) secreted factors over healthy endothelial progenitor cells (EPCs), in order to understand the mechanisms underlying the neovascularization and vascular remodeling properties assigned to these cells and to use...
ORGANISM(S): Homo sapiens (Human) 
2018-10-02 | PXD005465 | Pride
Lc-msms Endothelial progenitor cells Secretome 
UnknownAtherosclerotic Pre-Conditioning Affects the Paracrine Role of Circulating Angiogenic Cells Ex-Vivo.
Not available
S-EPMC7432497 | biostudies-literature
ProteomicsMouse Smooth muscle cell secretome with Anti-miR / pre-miR treatment
Overexpression and inhibition of miR-29 (pre-miR and anti-miR to miR-29b) in murine aortic smooth muscle cells, analysis of their secretome (conditioned media after serum starvation), n=3 for all four groups (pre-miR control, pre-miR-29b, anti-miR control, anti-miR-29b).
ORGANISM(S): Mus musculus (Mouse) 
2016-05-06 | PXD003938 | Pride
Mouse Smooth muscle cell Mir-29 
ProteomicsProteomics of endothelial cell secretome after exposure to calciprotein particles
Calciprotein particles (CPPs), assembled as a result of molecular interactions between fetuin-A and nascent calcium phosphate clusters, are indispensable scavengers of excessive Ca2+ and PO43– ions, thus representing an elegant mechanism which regulates mineral homeostasis. Generation of CPPs repres...
ORGANISM(S): Homo sapiens (Human) 
2024-10-24 | PXD055909 | Pride
Lc-ms/ms Inflammation Hcaec Calciprotein particles Hitaec Secretome 
UnknownSite-Specific Secretome Map Evidences VSMC-Related Markers of Coronary Atherosclerosis Grade and Extent in the Hypercholesterolemic Swine.
Not available
S-EPMC4561865 | biostudies-literature
UnknownEx vivo Ikkβ ablation rescues the immunopotency of mesenchymal stromal cells from diabetics with advanced atherosclerosis.
Not available
S-EPMC7898947 | biostudies-literature
UnknownSecreted proteins from carotid endarterectomy: an untargeted approach to disclose molecular clues of plaque progression.
Not available
S-EPMC3853772 | biostudies-literature
UnknownMetabolic Alterations Identified in Urine, Plasma and Aortic Smooth Muscle Cells Reflect Cardiovascular Risk in Patients with Programmed Coronary Artery Bypass Grafting.
Not available
S-EPMC8466954 | biostudies-literature
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