Data from ProteomeXchange, PXD ID: PXD001200. File: 1300809_AAS2set_10uM.mzml. Data publsihed as part of J Proteome Res. 2014 Sep 30 . From the Abstract: {{i}} ATP-binding proteins, including protein kinases, play essential roles in many biological and pathological processes and thus these proteins...
Macrophages are involved in the primary human host response to pathogens such as Candida albicans. After pathogen recognition by specific receptors, a cascade of signaling pathways is activated, leading to the production of cytokines, chemokines and antimicrobial peptides. ATP binding proteins are c...
Enterococcus faecium has emerged as a major nosocomial and opportunistic pathogen, increasingly associated with severe infections such as urinary tract infections, bacteraemia, and endocarditis. Notably, it exhibits intrinsic resistance to many antibiotics and has a remarkable capacity to acquire ad...
The opportunistic yeast pathogen Candida glabrata is recognized for its ability to acquire resistance during prolonged treatment with azole antifungals. Resistance to azoles is largely mediated by the transcription factor PDR1, resulting in the upregulation of ATP-binding cassette (ABC) transporter ...
Many protein activities are driven by ATP binding and hydrolysis. Here, we explore the ATP binding proteome of the model plant Arabidopsis thaliana using Acyl-ATP (AcATP) probes. These probes target ATP binding sites and covalently label lysine residues in the ATP binding pocket. Protein extracts we...
Arabidopsis is a host to the fungal powdery mildew pathogen, Erysiphe cichoracearum, and a nonhost to Blumeria graminis f.sp. hordei, the powdery mildew pathogenic on barley. A screen for mutants that allowed increased entry by this inappropriate or nonhost pathogen on Arabidopsis led to the identif...
