Autism. s-nitrosylation

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Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139 (1)
Departments of Biological Engineering and Chemistry, Massachusetts Institute of Technology, Cambridge, MA 02139, USA. (1)

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S-nitrosylation in Shank3 mutated mice

We tested the hypothesis that a mutated gene associated with human ASD would generate downstream effects in critical proteins that lead to modification of synaptic functions.

ORGANISM(S): Mus musculus (Mouse)

2018-10-02 | PXD006907 | Pride

Systems Biology Reveals S-Nitrosylation-Dependent Regulation of Mitochondrial Functions in Mice with Shank3 Mutation Associated with Autism Spectrum Disorder.

Not available

S-EPMC8224296 | biostudies-literature

Arsenic induces reversible nitrosative stress and behavioural changes in mice

Studies on exposure of mice to Arsenic, combined with unique tools developed in our laboratory to determine the consequences of NO formation in mouse brain and neuronal cell culture, will probe mechanistic pathways of nitrosative damage operable in behavioural development.

ORGANISM(S): Mus musculus (Mouse)

2021-09-08 | PXD012691 | Pride

Nitric oxide Brain Autism. s-nitrosylation Snotrap Arsenic

The role of nitric oxide in brain disorders: Autism spectrum disorder and other psychiatric, neurological, and neurodegenerative disorders.

Not available

S-EPMC7256645 | biostudies-literature

Proteomics of autism and Alzheimer's mouse models reveal common alterations in mTOR signaling pathway.

Not available

S-EPMC8448888 | biostudies-literature

Shank3 mutation in a mouse model of autism leads to changes in the S-nitroso-proteome and affects key proteins involved in vesicle release and synaptic function.

Not available

S-EPMC6614015 | biostudies-literature