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ProteomicsRapid processing of archival tissue samples for proteomic analysis using pressure-cycling technology
Advent of mass spectrometry based proteomics has revolutionized our ability to study proteins from biological specimenin a high-throughput manner. Unlike cell line based studies, biomedical research involving tissue specimen is often challenging due to limited sample availability. In addition, inves...
ORGANISM(S): Homo sapiens (Human) 
2018-01-08 | PXD006255 | Pride
Pressure cycling technology Mass spectrometry Barocycler 
ProteomicsABLE-SWATH - A Case Study and Methodology for OpenSWATH Parameter Optimization Using the ProCan90 Data Set and 45,810 Computational Analysis Runs
Proteomic methods typically involve lengthy, multi-step sample preparation protocols (14-16 hrs), especially for the lysis and digestion of solid tissue samples or cells. We developed a streamlined proteomic sample preparation protocol termed Accelerated Barocycler Lysis and Extraction (ABLE), that...
ORGANISM(S): Homo sapiens (Human) Rattus norvegicus (Rat) 
2019-01-21 | PXD010688 | Pride
Urea Sample preparation Clinical proteomics Swath Barocycler Sdc Pct 
ProteomicsASSESSING AUTOMATED SAMPLE PREPARATION TECHNOLOGIES FOR HIGH-THROUGHPUT PROTEOMICS OF FROZEN WELL CHARACTERIZED TISSUES FROM SWEDISH BIOBANKS
Large cohorts of carefully collected and stored clinical tissue materials play a central role in acquiring sufficient depth and statistical power to discover disease-related mechanisms and biomarkers of clinical significance. Manual preparation of such heterogeneous samples is labor intensive and re...
ORGANISM(S): Homo sapiens (Human) Rattus norvegicus (Rat) 
2018-11-27 | PXD010296 | Pride
Bravo assaymap Tissue Mass spectrometry Clinical proteomics Barocycler Bioruptor 
UnknownIsolation of functional mitochondria from rat kidney and skeletal muscle without manual homogenization.
Not available
S-EPMC3172370 | biostudies-literature
ProteomicsHeat ‘n Beat: A universal high-throughput end-to-end proteomics sample processing platform in under an hour
Clinical proteomics on solid tissue samples from human tumour biopsies present multiple challenges. These include limited sample availability, reducing endogenous protease activity and challenges with efficiently solubilising and digesting proteins for high throughput mass spectrometry while achievi...
ORGANISM(S): Homo sapiens (Human) Rattus norvegicus (Rat) 
2025-03-26 | PXD045405 | Pride
Sample preperation Proteomics High-throughput Heat n beat Universal Mass spec 
UnknownHigh-throughput proteomic sample preparation using pressure cycling technology.
Not available
S-EPMC9362583 | biostudies-literature
ProteomicsASSESSING AUTOMATED SAMPLE PREPARATION TECHNOLOGIES FOR HIGH-THROUGHPUT PROTEOMICS OF FROZEN WELL CHARACTERIZED TISSUES FROM SWEDISH BIOBANKS
Large cohorts of carefully collected and stored clinical tissue materials play a central role in acquiring sufficient depth and statistical power to discover disease-related mechanisms and biomarkers of clinical significance. Manual preparation of such heterogeneous samples is labor intensive and re...
ORGANISM(S): Rattus norvegicus (Rat) 
2018-11-27 | PXD011295 | Pride
Mass spectrometry clinical peoteomics 
UnknownPressure-assisted sample preparation for proteomic analysis.
Not available
S-EPMC3761939 | biostudies-literature
UnknownPressurized pepsin digestion in proteomics: an automatable alternative to trypsin for integrated top-down bottom-up proteomics.
Not available
S-EPMC3033671 | biostudies-literature
ProteomicsImplementation of data-independent acquisition mass spectrometry in metaproteomics of gut microbiota
A novel approach for metaproteomics that utilizes data independent acquisition (DIA) mass spectrometry which enables accurate and consistent quantification of peptides from samples with a complex microbial composition.
ORGANISM(S): Homo sapiens (Human) 
2019-11-25 | PXD008738 | Pride
Dda Lc Swath-ms Dia 
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