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ProteomicsInteraction between Pseudomonas aeruginosa and Achromobacter xylosoxidans: unravelling the molecular basis of competition affecting P. aeruginosa virulence
Proteomic analysis carried out to elucidate the molecular basis of P. aeruginosa virulence reduction during interaction with A. xylosoxidans
ORGANISM(S): Achromobacter xylosoxidans Pseudomonas aeruginosa 
2025-07-14 | PXD058911 | Pride
Proteomics Bacterial interaction Pathogens 
ProteomicsNelfinavir overcomes proteasome inhibitor resistance in multiple myeloma by modulating lipid bilayer composition and fluidity
Nelfinavir has broad anti-cancer activity precilincally as a single agent and in combination. Clinically, it is particularly effective in the therapy of proteasome inhibitor-refractory multiple myeloma. The broad anti-cancer mechanism of action of nelfinavir implies that it may interfere with very f...
ORGANISM(S): Homo sapiens (Human) 
2021-11-02 | PXD023260 | Pride
Proteasome inhibitors Affinity-purification Upr Crispr/cas9 Adipor2 Ezetimibe Nelfinavir Hiv-protease inhibitor Multiple myeloma 
ProteomicsProteasome beta2 and beta5 subunit inhibition by carfilzomib causes acute cardiomyocyte energy depletion and local angiotensin synthesis
Treatment of multiple myeloma (MM) with the second-generation proteasome inhibitor (PI) carfilzomib (CFZ) is associated with higher incidence of cardiovascular adverse events compared to first-generation PI bortezomib (BTZ). CFZ and BTZ inhibit the individual proteasome subunits beta1, beta2 and bet...
ORGANISM(S): Mus musculus (Mouse) 
2025-08-01 | PXD029077 | Pride
Redox pathways Contractility Cardiomyocytes Carfilzomib Energy metabolism Proteasome 
TranscriptomicsIn vivo gene expression in granulosa cells during pig terminal follicular development.
The aim of this study is the identification of genes and gene networks involved in pig ovarian follicular development. cDNA nylon micro-arrays (2849 sequenced clones) were designed from different libraries : four subtractive suppressive hybridization libraries (generated from small versus large and ...
ORGANISM(S): Sus scrofa 
2008-04-30 | E-GEOD-5798 | biostudies-arrayexpress
UnknownLinking Primary and Secondary Care after Psychiatric Hospitalization: Comparison between Transitional Case Management Setting and Routine Care for Common Mental Disorders.
Not available
S-EPMC4889580 | biostudies-literature
TranscriptomicsComparative genomic hybridization by array of 121 paired tumor and non-tumor tissue samples from patients with non-small cell lung carcinoma to gain a systems biology insight into the current clinical classification
Non-small cell lung cancer (NSCLC), a leading cause of cancer deaths, represents a heterogeneous group of neoplasms, mostly comprising squamous cell carcinoma (SCC), adenocarcinoma (AC) and large-cell carcinoma (LCC). The aim of this study was to gain a systems biology insight into the current clini...
ORGANISM(S): Homo sapiens 
2013-12-11 | E-MTAB-1133 | biostudies-arrayexpress
UnknownRare EGFR exon 18 and exon 20 mutations in non-small-cell lung cancer on 10 117 patients: a multicentre observational study by the French ERMETIC-IFCT network.
Not available
S-EPMC3868323 | biostudies-literature
TranscriptomicsIn vivo gene expression in granulosa cells during pig terminal follicular development- oligo
These vector oligonucleotide hybridizations were performed to determine the quality of the spotting process. EST with low signal values of the vector array were excluded from the analysis, since they probably were mis-amplified or mis-spotted Keywords: spotting control cDNA arrays (GPL3978) were fi...
ORGANISM(S): Sus scrofa 
2008-04-30 | E-GEOD-5797 | biostudies-arrayexpress
UnknownNicosulfuron Degradation by an Ascomycete Fungus Isolated From Submerged <i>Alnus</i> Leaf Litter.
Not available
S-EPMC6305708 | biostudies-literature
ProteomicsMicro cell surface proteomics myeloma
The myeloma cell surface proteome (“surfaceome”) not only determines tumor interaction with the microenvironment but serves as an emerging arena for therapeutic development. Here, we use glycoprotein capture proteomics to first define surface markers most-enriched on myeloma when compared to B-cell ...
ORGANISM(S): Homo sapiens (Human) 
2022-05-27 | PXD022553 | Pride
Cell surface Plasma cell Multiple myeloma 
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