Sort   by:  
 Page size 
ProteomicsSOURCES OF BIASES IN THE IN VITRO TESTING OF NANOMATERIALS: THE ROLE OF BIOMOLECULAR CORONA
The biological fate of nanomaterials (NMs) is driven by the specific interactions that biomolecules, naturally adhering onto their surface, engage with cell membrane receptors and intracellular organelles. The molecular composition of this layer, called biomolecular corona (BMC), depends on both the...
ORGANISM(S): Homo sapiens (Human) 
2024-05-31 | PXD046988 | Pride
Graphene Gold nanoparticles Biomolecular corona Nanomaterials 
TranscriptomicsBiomolecular Condensate Coronas from Nanoparticle Intracellular Processing Are Transferred Between Cells Allowing Cytosolic and Nuclear Access
We describe ‘nanomaterial-biological hybrid complexes’ composed partly of an engineered nanoparticle core and formed partly by active processes within cells. Thus magnetic nanoparticles are internalized by cells, undergo active biomolecular deposition to form a new overlaid cell-derived corona layer...
ORGANISM(S): Homo sapiens 
2026-04-16 | E-MTAB-16398 | biostudies-arrayexpress
ProteomicsDeep Plasma Proteome Profiling by Modulating Single Nanoparticle Protein Corona with Small Molecules
The protein corona, a dynamic biomolecular layer that forms on nanoparticle (NP) surfaces upon exposure to biological fluids is emerging as a valuable diagnostic tool for improving plasma proteome coverage analyzed by liquid chromatography-mass spectrometry (LC-MS/MS). Here, we show that spiking pho...
ORGANISM(S): Homo sapiens (Human) 
2024-10-15 | PXD053359 | Pride
Protein corona Top down proteomics Human plasma Bottom up proteomics Nanoparticles 
ProteomicsMass spectrometry-based top-down proteomics in nanomedicine: proteoform-specific measurement of protein corona
Conventional mass spectrometry (MS)-based bottom-up proteomics (BUP) analysis of protein corona [i.e., an evolving layer of biomolecules, mostly proteins, formed on the surface of nanoparticles (NPs) during their interactions with biomolecular fluids] enabled nanomedicine community to partly identif...
ORGANISM(S): Homo sapiens (Human) 
2024-10-15 | PXD050779 | Pride
Protein corona Top-down proteomics Nanomedicine Plasma Proteoform 
ProteomicsInflammatory disease progression shapes nanoparticle biomolecular corona-mediated immune activation profiles
Polymeric nanoparticles (NPs) have emerged as promising tools for immunomodulation in various disease contexts. The interactions between the NP surface and plasma-resident biomolecules result in the formation of a biomolecular corona (BC), which varies patient-to-patient and as a function of disease...
ORGANISM(S): Mus musculus (Mouse) 
2025-01-17 | PXD050918 | Pride
Biomolecular corona Inflammation Immunomodulation Nanoparticles Immunogenicity 
UnknownCoagulation Matters: ATIII-Enriched Biomolecular Corona Enhances the Hemocompatibility of PEG Nanoparticles.
Not available
S-EPMC12447026 | biostudies-literature
UnknownBiomolecular Corona Stability in Association with Plasma Cholesterol Level.
Not available
S-EPMC9370777 | biostudies-literature
UnknownNanoparticle Biomolecular Corona-Based Enrichment of Plasma Glycoproteins for N-Glycan Profiling and Application in Biomarker Discovery.
Not available
S-EPMC9047655 | biostudies-literature
UnknownAquatic organisms modulate the bioreactivity of engineered nanoparticles: focus on biomolecular corona.
Not available
S-EPMC9437328 | biostudies-literature
UnknownInflammatory disease progression shapes nanoparticle biomolecular corona-mediated immune activation profiles.
Not available
S-EPMC11754911 | biostudies-literature
Sort   by:  
 Page size