Sort   by:  
 Page size 
TranscriptomicsRNASeq analysis of brown bear (Ursus arctos) skin tissue during active state and hibernation
Transcriptomic analysis of the brown bear (Ursus arctos) tissues during both active and inactive phases has unveiled significant differential gene expression, with thousands of genes exhibiting altered activity in all studied tissues (muscle, liver, adipose...). Nevertheless, transcriptional analyse...
ORGANISM(S): Ursus arctos 
2025-09-05 | E-MTAB-14479 | biostudies-arrayexpress
ProteomicsBiochemical Foundations of Health and Energy Conservation in Hibernating Free-Ranging Subadult Brown Bear Ursus arctos
Brown bears (Ursus arctos) hibernate for 5-7 months without eating, drinking, urinating and defecating at a metabolic rate of only 25% of the summer activity rate. Nonetheless, they emerge healthy and alert in spring. We analyzed the physiological adaptations for hibernation by comparing the proteom...
ORGANISM(S): Ursus arctos arctos (European brown bear) 
2016-09-27 | PXD003946 | Pride
Ursus arctos Brown bear Proteomics Hibernation Lc-ms/ms 
ProteomicsQuantitative proteomics of brown bear muscle during hibernation
During hibernation, the physiology of bears is characterized by strong metabolic depression. In skeletal muscles, lipids are used as the main energy fuels although their oxidation rate is reduced, and glycolysis appears maintained likely feeding the Cori cycle. For a better knowledge on proteome rem...
ORGANISM(S): Ursus arctos (Brown bear) (Grizzly bear) 
2026-03-02 | PXD060503 | Pride
Lc-msms Metabolic depression Bear Hibernation Muscle 
ProteomicsBrown bear skeletal muscle quantitative LC-MSMS
Muscle atrophy is one of the main deleterious consequences of ageing and physical inactivity. Although basic knowledge regarding the underlying mechanisms of muscle atrophy is continuously growing, there are still no efficient therapeutic strategies for its prevention and treatment. Hibernating bear...
ORGANISM(S): Ursus arctos (Brown bear) (Grizzly bear) 
2019-05-14 | PXD004908 | Pride
Lc-msms Skeletal muscle Hibernation Bears 
ProteomicsPlasma proteomics data of hibernating and active wild Scandinavian brown bears
Here we provide mass-spectrometry based plasma proteomics data of hibernating and active wild Scandinavian brown bears (Ursus arctos arctos). The brown bear hibernates for half the year. Despite obesity and the prolonged period of inactivity, bears show no signs of the harmful effects associated wi...
ORGANISM(S): Ursus arctos arctos (European brown bear) 
2021-12-21 | PXD030482 | Pride
Ursus arctos Brown bear Plasma Proteomics Hibernation Lc-ms/ms 
UnknownA protocol for the isolation and cultivation of brown bear (Ursus arctos) adipocytes.
Not available
S-EPMC5023558 | biostudies-literature
GenomicsAncient environmental genome reveals a migratory brown bear individual in Early Holocene Scandinavia
Environmental ancient brown bear genome FISK2006
PRJEB88808 | ENA
ProteomicsBrown bear skeletal muscle 2D-DIGE-LC-MSMS
Muscle atrophy is one of the main deleterious consequences of ageing and physical inactivity. Although basic knowledge regarding the underlying mechanisms of muscle atrophy is continuously growing, there are still no efficient therapeutic strategies for its prevention and treatment. Hibernating bear...
ORGANISM(S): Ursus arctos arctos (European brown bear) 
2019-05-14 | PXD011687 | Pride
Lc-msms Skeletal muscle Hibernation Bears 2d-dige 
UnknownDiet of the brown bear in Himalaya: Combining classical and molecular genetic techniques.
Not available
S-EPMC6932756 | biostudies-literature
ProteomicsLC-MSMS analysis of HFF1 cells exposed to bear and bovine serum
The serum of hibernating bears has been shown to exhibit cytoprotective, anticatabolic effects when applied to human or mouse skeletal muscle cells. It is also able to reduce mitochondrial respiration in cells obtained from bear adipose tissue. Its action notably might involve reprogramming of trans...
ORGANISM(S): Homo sapiens (Human) 
2025-12-08 | PXD069199 | Pride
Serum Hibernation Quantitative proteomics Fibroblast 
Sort   by:  
 Page size