Sort   by:  
 Page size 
ProteomicsInvestigating the effect of fluid flow on glomerular cell-derived matrix
The glomerular basement membrane has a complex composition and structure in vivo. In vitro models of the glomerular capillary wall have been developed using microfluidic and perfusion systems, however, how the extracellular matrix alters under static and flow conditions has not yet been investigate...
ORGANISM(S): Homo sapiens (Human) 
2026-02-02 | PXD044226 | Pride
Glomerular matrix Microfluidic bioreactor Glomerular filtration barrier 
ProteomicsHuman glomerular extracellular matrix analysed by LC-MSMS
Extracellular matrix proteins were isolated from human glomeruli and analysed by LC-MSMS
ORGANISM(S): Homo sapiens (Human) 
2014-01-22 | PXD000456 | Pride
Human Glomerulus Kidney Extracellular matrix 
ProteomicsHuman glomerular cell-derived extracellular mantrix
We isolated the extracellular matrix from human podocytes and endothelial cells in monoculture and coculture and analysed the matrix proteins by mass-spectrometry. The glomerular basement membrane (GBM) is a specialized extracellular matrix (ECM) compartment within the glomerulus and is known to con...
ORGANISM(S): Homo sapiens (Human) 
2014-01-29 | PXD000643 | Pride
Coculture Endothelial cells Pododcytes 
ProteomicsProteomic analysis of healthy and hyperglycemic murine fetal kidneys
Alteration of kidney morphogenesis in diabetic pregnancies is poorly described, especially changes in the extracellular matrix (ECM) and glomerular basement membrane (GBM during glomerulogenesis. Addressing the ECM proteome, or matrisome, in the mouse fetal kidney in a healthy and diabetic environme...
ORGANISM(S): Mus musculus (Mouse) 
2021-10-13 | PXD025874 | Pride
Mass spectrometry Basement membrane Enrichment Kidney Extracellular matrix Diabetes 
ProteomicsIntegrin adhesion complexes formed on different basement membrane ligands
Adhesion complexes isolated from cells in culture. Podocytes were attached to different extracellular matrix ligands and adhesion complex isolated.
ORGANISM(S): Homo sapiens (Human) 
2020-03-09 | PXD017913 | Pride
Podocyte Ab Extracellular matrix ligand. Integrins Adhesions Rpe19 
ProteomicsMouse kidney glomerular extracellular matrix LC-MSMS
Across the spectrum of human disease there are significant changes in the composition and organisation of extracellular matrix (ECM). Furthermore, disease severity can vary according to race and sex, yet mechanisms for these variations are unclear. Using the kidney glomerulus as a model system, we t...
ORGANISM(S): Mus musculus (Mouse) 
2016-07-09 | PXD000811 | Pride
Lc-msms Mouse Kidney Glomerular Extracellular matrix 
Sort   by:  
 Page size