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Centrioles are evolutionary conserved macromolecular structures that are fundamental for templating the formation of cilia and flagella, as well as for assembling centrosomes. Centrioles are nine-fold symmetrical microtubule-based cylindrical structures, which have three regions that can be clearly ...
ORGANISM(S): Chlamydomonas reinhardtii 
2018-06-12 | PXD005818 | Pride
Differential gene expression in embryonic lung and small intestine after epithelial deletion of centrioles
The centriole duplication cycle must be tightly controlled and coordinated with the chromosome cycle to maintain a proper number of centrioles in cells. Aberrations in centriole biogenesis can lead to cancer, developmental disorders and ciliopathies, yet the molecular determinants of centriole numbe...
ORGANISM(S): Homo sapiens (Human) 
2025-12-02 | PXD037043 | Pride
Epithelial specific disruption of centrioles but not cilia results in severe phenotype in the lung but not in the intestine. Compare gene expression in lung and small intestine of control (ShhCre Cenpj+/lox), epithelial centriole disrupted (ShhCre Cenpj-/lox), and epithelial cilia disrupted (ShhCre ...
ORGANISM(S): Mus musculus 
2021-12-31 | GSE188585 | GEO
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