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MetabolomicsCFAP418 participates in membrane-associated cellular processes through binding lipids during ciliogenesis
Not available
ORGANISM(S): Mus musculus 
ST002162 | MetabolomicsWorkbench
GenomicsCoordinated genomic control of ciliogenesis and cell movement by Rfx2
We have performed a systems-level analysis of the RFX/Daf-19 family transcription factor, Rfx2. Using a combination of high-throughput sequencing of Rfx2-regulated transcripts and chromosomal binding sites, we provide a comprehensive accounting of the target genes by which Rfx2 controls ciliogenesis...
ORGANISM(S): Xenopus laevis 
2013-12-12 | E-GEOD-50593 | biostudies-arrayexpress
ProteomicsBAG3 suppresses ciliogenesis by regulating levels of OFD1
By regulating several hallmarks of cancer, BAG3 exerts oncogenic functions in a wide variety of malignant diseases including glioblastoma (GBM) and triple-negative breast cancer (TNBC). Here we performed global proteomic/phosphoproteomic analyses of Crispr/Cas9-mediated isogenic BAG3 knockouts of th...
ORGANISM(S): Homo sapiens (Human) 
2021-06-21 | PXD024802 | Pride
Phosphoproteome Ofd1 Ciliogenesis Bag3 Glioblastoma cells Proteome 
ProteomicsLRRK2-RAB12 Complex Suppresses Primary Ciliogenesis and Regulates Centrosome Homeostasis in Astrocytes
Leucine-rich repeat kinase 2 (LRRK2) phosphorylates a subset of RAB GTPases and this phosphorylation is elevated by Parkinson’s disease (PD)-linked mutations of LRRK2. However, the precise function of the specific RAB GTPase targeted by LRRK2 signaling remains to be elucidated. Here we solve the str...
ORGANISM(S): Mus musculus (Mouse) 
2025-01-18 | PXD048732 | Pride
Structure of lrrk2-rab12 protein complex Proteomics Lrrk2 Ciliogenesis Centrosome homeostasis Parkinson’s disease Tandem mass tag 
GenomicsSoft matrix promotes ciliogenesis in human retinal pigment epithelial cells
Soft matrix promotes ciliogenesis in human retinal pigment epithelial cells
PRJNA1483545 | ENA
ProteomicsCentriolar satellites expedite mother centriole remodeling to promote ciliogenesis
Centrosomes are orbited by centriolar satellites, dynamic multiprotein assemblies nucleated by PCM1. To study the requirement for centriolar satellites, we generated mice lacking PCM1. Pcm1-/- mice display partially expressive perinatal lethality with survivors exhibiting hydrocephalus, oligospermia...
ORGANISM(S): Mus musculus (Mouse) 
2023-05-10 | PXD031920 | Pride
Mtecs Cilia 
GenomicsmiR-200 represses primary ciliogenesis by direct repression of DZIP1
miR-200 represses primary ciliogenesis by direct repression of DZIP1
PRJNA1393074 | ENA
GenomicsEffect of loss of ciliogenesis on myoblast quiescence
Effect of loss of ciliogenesis on myoblast quiescence
PRJNA434444 | ENA
TranscriptomicsMulticilin promotes centriole assembly and ciliogenesis during multiciliate cell differentiation.
Analysis of epithelial explants injected with the intracellular domain of Notch (ICD) alone, to block the formation of multiciliate cells, or with Dexamethasone inducible Multicilin (MCI-HGR) to induce the formation of ectopic multiciliate cells. MCI-HGR plus ICD injected samples were compared to I...
ORGANISM(S): Xenopus laevis 
2012-03-01 | E-GEOD-32452 | biostudies-arrayexpress
GenomicsCiliogenesis and autophagy are coordinately regulated by EphA2 in the cornea to maintain proper epithelial architecture
Ciliogenesis and autophagy are coordinately regulated by EphA2 in the cornea to maintain proper epithelial architecture
PRJNA730891 | ENA
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