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Cell requires optimal amount of nutrients for the synthesis of macromolecules like lipid, protein and nucleotides. There is a very limited knowledge about how cells maintain homeostasis in excess nutrients. By using Yeast as a model system we have shown that some aminoacids are toxic at higher conce...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2019-08-13 | PXD014880 | Pride
Cell requires optimal amount of nutrients for the synthesis of macromolecules like lipid, protein and nucleotides. There is a very limited knowledge about how cells maintain homeostasis in excess nutrients. By using Yeast as a model system we have shown that some aminoacids are toxic at higher conce...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2019-08-13 | PXD014859 | Pride
In the context of studying the role of the COP9 signalosome (CSN) in neuroinflammation and ischemic neuronal damage, we studied the effect of the cullin NEDDylation state-modifying drugs MLN4924 and CSN5i-3 in BV2 microglial cells, an immortalized murine cell line featuring many of the characteristi...
ORGANISM(S): Mus musculus (Mouse) 
2023-10-24 | PXD044650 | Pride
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