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Chlamydia trachomatis is an obligate intracellular pathogen that replicates within a specialized membrane-bound compartment, the inclusion. Chlamydia species express a unique class of effectors, Incs, which are translocated from the bacteria by a Type III secretion system and are inserted into the i...
ORGANISM(S): Chlamydia trachomatis Chlamydia trachomatis Homo sapiens (Human) 
2025-03-31 | PXD028543 | Pride
Recognition of pathogen-derived foreign nucleic acids is central to innate immune defense. This requires discrimination between structurally highly similar self and nonself nucleic acids to avoid aberrant inflammatory responses as in the autoinflammatory disorder Aicardi-Goutires syndrome (AGS). How...
ORGANISM(S): Homo sapiens (Human) 
2023-02-06 | PXD035182 | Pride
Genome-wide transcriptional profiling of Bj110 cells treated with P6 (20 uM for 24 h). Three independent biological materials were prepared for cells treated with P6 or DMSO (vehicle control). A total 6 arrays which includes dye swap were analyzed.
ORGANISM(S): Bradyrhizobium japonicum USDA 110 
Siglec-7 is a member of Siglec family of glycan recognition proteins involved in the regulation of natural killer (NK) cell activities. We found Siglec-7 ligand is highly expressed on JVM-3, a B cell chronic lymphocytic leukemia (B-CLL) cell line. In this experiment, we attempted at identifying th...
ORGANISM(S): Homo sapiens (Human) 
2022-05-31 | PXD024690 | Pride
Bacteria modify expression of different types of terminal oxidase in response to oxygen availability. Corynebacterium glutamicum, a facultative anaerobic bacterium in Actinobacteria, possesses aa3-type cytochrome c oxidase and cytochrome bd-type quinol oxidase, the latter of which is induced upon ox...
ORGANISM(S): Corynebacterium glutamicum 
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