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MetabolomicsL-fucose and fucoidan alleviate high-salt diet-promoted acute inflammation

Excessive salt intake is a widespread health issue observed in almost every country around the world. A high salt diet (HSD) has a strong correlation with numerous diseases, including hypertension, chronic kidney disease and autoimmune disorders. However, the mechanisms underlying HSD-promotion o...

2024-02-21 | MTBLS9134 | MetaboLights
ProteomicsHeLa, HEK293T and mouse lung, heart and spleen LC-MS/MS
Proteins are ubiquitously modified with glycans of varied chemical structures via distinct glycosidic linkages, making the landscape of protein glycosylation challenging to map. Profiling of intact glycopeptides with mass spectrometry (MS) has recently emerged as a powerful tool for revealing match...
ORGANISM(S): Mus musculus (Mouse) 
2025-02-12 | PXD039144 | Pride
Hela Mouse lung Heart Hek293t Spleen Lc-ms/ms 
ProteomicsThe influence of IL-1β and TNF-α on the tenogenic differentiation of human periodontal ligament stem cells via global proteomic analysis
The hPDLSCs were cultured in the tenogenic medium treated with 0.1 ng/ml IL-1β or 10 ng/ml TNF-α for 7 days. Total proteins were isolated from the collected cell samples. Subsequently, the LFQ-based proteomic analysis was conducted for the extracted proteins in each group as established procedures...
ORGANISM(S): Homo Sapiens 
PXD056585 |
ProteomicsThe data of protein expression of hMSCs in Soft, Medium and Stiff group
After treated with different stiffness and macrophage paracrine signals at the same stiffness for 3 days, MSCs were harvested for proteomic analysis. The label-free quantification (LFQ) based proteomic analysis was performed for global protein expressions.
ORGANISM(S): Homo Sapiens 
2022-07-21 | PXD035511 |
UnknownAssociations of ACE I/D and AGTR1 rs5182 polymorphisms with diabetes and their effects on lipids in an elderly Chinese population.
Not available
S-EPMC11290002 | biostudies-literature
UnknownSmall size fullerenol nanoparticles suppress lung metastasis of breast cancer cell by disrupting actin dynamics.
Not available
S-EPMC6015447 | biostudies-literature
ProteomicsCys-SH based quantitative redox proteomics of salt induced response in sugar beet monosomic addition line M14
Salt stress is a major abiotic stress that limits plant growth, development and productivity. Studying the molecular mechanisms of salt stress tolerance may help to enhance crop productivity. Sugar beet monosomic addition line M14 exhibits tolerance to salt stress. In this work, the changes in the ...
ORGANISM(S): Beta vulgaris subsp. vulgaris 
2021-12-30 | PXD027550 | Pride
Molecular mechanisms Sugar beet m14 line Salt stress Redox proteomics Iodotmtraq 
UnknownManganese deception on graphene and implications in catalysis.
Not available
S-EPMC6157277 | biostudies-literature
UnknownRationale and design of a randomised double-blind 2×2 factorial trial comparing the effect of a 3-month intensive statin and antiplatelet therapy for patients with acute mild ischaemic stroke or high-risk TIA with intracranial or extracranial atherosclerosis (INSPIRES).
Not available
S-EPMC10359782 | biostudies-literature
ProteomicsMultifunctional polyphenol-based silk hydrogel alleviates oxidative stress and enhances endogenous regeneration of osteochondral defects
The native microenvironment following osteochondral defect is not permissive for its endogenous regeneration. A variety of hydrogels have been developed to regulate cell behaviors; however, there is still a lack of hydrogels with multifunctional properties that can provide a supportive microenvironm...
ORGANISM(S): Rattus Rattus 
2021-11-28 | PXD030026 |
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