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UnknownThe role of randomization inference in unraveling individual treatment effects in early phase vaccine trials.
Not available
S-EPMC11466280 | biostudies-literature
ProteomicsEMP1 preserves hematopoietic stem cell potential under homeostasis and radiation-induced injury by alleviating ER stress
To illustrate EMP1-interacting proteins, we performed co-immunoprecipitation (co-IP) followed by mass spectrometry using HSPCs (Lin-c-Kit+) to characterize protein interactomes of EMP1. Murine HSPCs (Lin-c-Kit+) were infected with retrovirus to force EMP1 overexpression (with HA tag). Then IgG or HA...
ORGANISM(S): Mus musculus (Mouse) 
2025-03-13 | PXD055884 | Pride
Hspcs Emp1 
ProteomicsTargeting nucleoporin 214 selectively eliminates leukemia stem cells
To profile the E3 ligase associated with NUP214 neddylation, the NUP214 co-IP sample in THP-1 cells were examined by mass spectrometry.
ORGANISM(S): Homo sapiens (Human) 
2025-07-26 | PXD054462 | Pride
Nup214 Leukemia stem cells 
ProteomicsTargeting nucleoporin 214 selectively eliminates leukemia stem cells
To illustrate NUP214-interacting proteins, we performed co-immunoprecipitation (co-IP) followed by mass spectrometry using MLL-AF9-driven LSCs to characterize protein interactomes of NUP214.
ORGANISM(S): Mus musculus (Mouse) 
2025-07-26 | PXD054438 | Pride
Nup214 Leukemia stem cells 
ProteomicsTargeting nucleoporin 214 selectively eliminates leukemia stem cells
LSCs from MLL-AF9-driven Nup214fl/fl and Nup214fl/fl,Tie2-Cre AML mice were sorted, followed by further proteomic assay.
ORGANISM(S): Mus musculus (Mouse) 
2025-07-26 | PXD054471 | Pride
Nup214 Leukemia stem cells 
ProteomicsTargeting KPNB1 suppresses DNA damage repair in AML cells by inhibiting HMGB2 nuclear translocation
To gain insight into the potential cargo proteins mediated by KPNB1, the nuclear fraction of DMSO- and IPZ-treated NB-4 cells were isolated and then subjected to mass spectrometry analysis.
ORGANISM(S): Homo sapiens (Human) 
2025-01-03 | PXD056172 | Pride
Kpnb1 Nb-4 
UnknownThe role and mechanism of "eight famous herbals in Zhejiang" in cancer via network pharmacology and experimental validation.
Not available
S-EPMC11612504 | biostudies-literature
ProteomicsProteomic sequencing of Akkermansia muciniphila (Akk) and Akkermansia muciniphila-derived extracellular vesicles (Akk-EVs)
We conducted comparative proteomic sequencing of Akkermansia muciniphila (Akk) and its extracellular vesicles (Akk-EVs) to identify functional protein components within Akk-EVs responsible for alleviating disease progression
ORGANISM(S): Trypanosoma brucei Akkermansia muciniphila 
2026-06-08 | PXD062069 | Pride
Akk-evs Akkermansia muciniphila Proteomic sequencing 
ProteomicsUrsodeoxycholic acid promoted TGF-β degradation
MS analysis of proteins interacting with PKA and TGF-β1 in HEK293T cells. MS analysis of immunoprecipitated TGF-β1 in HEK293T cells with TGF-β1 overexpression.
ORGANISM(S): Mus musculus (Mouse) 
2022-06-28 | PXD031801 | Pride
Tgf-β1 Pka Phosphorylation modification 
MetabolomicsIntegrated microbiome-metabolome-genome axis data of Laiwu and Lulai pigs
Excessive fat deposition can trigger metabolic diseases, and it is crucial to identify factors that can break the link between fat deposition and metabolic diseases. Healthy obese Laiwu pigs (LW) are high in fat content but resistant to metabolic diseases. In this study, we compared the fecal microb...
2023-04-20 | MTBLS3977 | MetaboLights
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