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Chroococcidiopsis sp. SAG-NB-4 Genome sequencing
Analysis of chromosomal structual aberratons in NB-4 cell line
Gene expression analisys of GD2+ cells from metastatic NB, unselected bone marrow from metastatic NB, primary tumors from stage 4 NB (alive and dead at 5 years of follow-up) and primary tumor from localized NB
In neuroblastoma (NB) patients metastasis are the main cause of death, thus understanding the biological and genetic features of the metastatic NB cells is needed to reach efficient target-based therapies for high risk patients. In recent years, several prognostic signatures derived from gene expres...
ORGANISM(S): Homo sapiens 
We have used an IGR-N-91 parental cell line established from an involved bone marrow harvested from a high-risk NB (stage 4-NB, 8 year-old boy). These IGR-N-91 neuroblasts were injected subcutaneously into nude mice and a Primary Tumor Xenograft (PTX) was isolated whilst metastatic neuroblasts were...
ORGANISM(S): Homo sapiens 
Cisplatin (CDDP) is a widely used agent in the treatment of neuroblastoma. Unfortunately, the development of acquired chemoresistance limits its clinical use. To gain a detailed understanding of the mechanisms underlying the development of such chemoresistance, we comparatively analysed established ...
ORGANISM(S): Homo sapiens (Human) 
2019-01-02 | PXD012132 | Pride
To gain insight into the potential cargo proteins mediated by KPNB1, the nuclear fraction of DMSO- and IPZ-treated NB-4 cells were isolated and then subjected to mass spectrometry analysis.
ORGANISM(S): Homo sapiens (Human) 
2025-01-03 | PXD056172 | Pride
This Hi-C experiment was a part of a research which analyzed chromosomal structural aberrations in hematological malignancies. First, the author conducted comprehensive detection of fusion transcripts in RNA-seq data of DSMZ’s 99 cell lines, and then picked up cell lines with characteristic complex ...
ORGANISM(S): Homo sapiens 
2024-06-15 | GSE235154 | GEO
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