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UnknownMiRKAT-MC: A Distance-Based Microbiome Kernel Association Test With Multi-Categorical Outcomes.
Not available
S-EPMC9010828 | biostudies-literature
ProteomicsDIA-PASEF–based total proteome profiling of HeLa cells expressing nuclear or cytosolic p62 condensates
Cells were lysed in 6 M guanidine-HCl, 100 mM HEPES-NaOH, pH7.5, 10 mM TCEP, and 40 mM CAA. The lysates were dissolved by heating and sonication, followed by centrifugation at 20,000 × g for 15 min at 4 °C. The supernatants were recovered, and proteins (20 µg each) were purified by the SP3 method an...
ORGANISM(S): Homo Sapiens (human) 
2025-12-30 | PXD072518 | JPOST Repository
UnknownIncreased expression of EZH2 indicates aggressive potential of urothelial carcinoma of the bladder in a Chinese population.
Not available
S-EPMC6290761 | biostudies-literature
ProteomicsDIA-PASEF–based FLAG-IP proteomic analysis of nuclear or cytosolic p62 condensates in HeLa cells
Cells were cross-linked with 0.1% formaldehyde for 10 min at 25 °C and quenched with 100 mM glycine. After washing with HBS (20 mM HEPES-NaOH, pH 7.5, 150 mM NaCl), cells were lysed in HEPES-RIPA buffer (20 mM HEPES-NaOH, pH 7.5, 150 mM NaCl, 1 mM MgCl₂, 1 mM EGTA, 1% NP-40, 0.25% sodium deoxycholat...
ORGANISM(S): Homo Sapiens (human) 
2025-12-30 | PXD072519 | JPOST Repository
ProteomicsURI alleviates tyrosine kinase inhibitors-induced ferroptosis by reprogramming lipid metabolism in p53 wild-type liver cancers. HEK293T cells were transfected with His-URI plasmid before anti-His immunoprecipitation and gel cutting. LC-MS/MS was performed to identify URI potential binding proteins.
URI keeps low levels of p53 in a TRIM28-MDM2 dependent manner, maintains SCD1 activity and accumulation of MUFAs, and subsequently promotes resistance to TKIs in cancer cell. URI-p53-SCD1 axis mediates resistance of TKIs and may explain why p53-wild type HCC still showed intrinsic resistance to TKIs...
ORGANISM(S): Homo sapiens (Human) 
2023-09-15 | PXD045407 | Pride
Uri 
ProteomicsProteomic Analysis of Human Nucleus Pulposus in Young and Elderly Individuals Using TMT Quantification
This project investigates the differential proteomic profiles of human nucleus pulposus samples from young and elderly individuals. Using Tandem Mass Tag (TMT) quantification, we aim to identify and compare protein expression differences between the two groups. The research explores the biological i...
ORGANISM(S): Homo Sapiens 
2025-06-23 | PXD065307 |
ProteomicsIntegrated tissue proteome and metabolome reveal key elements and regulatory pathways in cutaneous squamous cell carcinoma
we took advantage of nanoscale liquid chromatography and quadrupole time-of-flight tandem mass spectrometry (nanoLC/Q-TOF-MS/MS) and ultraperformance LC/Q-TOF-MS/MS techniques on cancer and the corresponding paracancerous tissues from 20 CSCC patients for integrated proteomic and metabolomic analyse...
ORGANISM(S): Homo Sapiens 
2021-01-20 | PXD023716 |
ProteomicsIntegrative Comparative Proteomics Identifies Core Differentially Expressed Proteins and Pathways for Drought Tolerance by Exploiting Contrasting Rice Varieties
More tightly coordinated response was revealed at the protein level in the tolerant varieties by proteomic analysis. Carbohydrate metabolism, redox homeostasis and protein transport were found activated in the tolerant varieties in functional enrichment analysis; while photosynthesis was suppressed....
ORGANISM(S): Oryza Sativa 
2026-01-11 | PXD072923 |
ProteomicsAnalyze the post-translation modification of UVRAG
To explore the role of post-translational modification on UVRAG, we used tandem mass spectrometry (MS/MS) to analyze the UVRAG from cells.
ORGANISM(S): Homo Sapiens 
2022-06-14 | PXD034521 |
ProteomicsMass spectrometric profiling of intermolecular disulfide bonds between ROMO1 and its targets
Mass spectrometric profiling of intermolecular disulfide bonds between ROMO1 and its targets
ORGANISM(S): Homo Sapiens 
2024-06-11 | PXD053027 |
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