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Protein regulation of metabolic processes is foundational to biology. Here we develop a mass spectrometry-based approach that leverages genetic diversity to nominate functional relationships between 285 metabolites and 11,868 proteins in living tissues. This Metabolite Protein Covariation Architectu...
ORGANISM(S): Mus musculus (Mouse) 
2025-07-28 | PXD065355 | Pride
Multiple bacterial genera take advantage of the multifunctional utoprocessing repeats-in-toxin (MARTX) toxin to invade host cells1. Secretion of the MARTX toxin by Vibrio vulnificus, a deadly opportunistic pathogen that causes primary septicemia, the precursor of sepsis2-5, is a major driver of inf...
ORGANISM(S): Homo sapiens (Human) 
2024-07-05 | PXD047927 | Pride
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