Sort   by:  
 Page size 
MetabolomicsIdentification of Biomarkers Using Metabolomics: From Chronic Non-Atrophic Gastritis and Chronic Atrophic Gastritis to Gastric Cancer

Gastric cancer (GC) is a severe malignancy characterized by late diagnosis, poor prognosis and low survival rates. Its progression is often linked to chronic non-atrophic gastritis (CNAG) and chronic atrophic gastritis (CAG), which show atypical symptoms. Identifying biomarkers for CNAG, CAG and ...

2026-09-29 | MTBLS12186 | MetaboLights
TranscriptomicsMepenzolate bromide displays beneficial effects in a mouse model of chronic obstructive pulmonary disease
For the clinical treatment of chronic obstructive pulmonary disease (COPD), it is important not only to improve the airflow limitation by bronchodilation but also to suppress emphysema by controlling inflammation. In this study, we have screened for compounds that prevent elastase-induced airspace ...
ORGANISM(S): Mus musculus 
2013-11-13 | E-GEOD-50836 | biostudies-arrayexpress
MetabolomicsChronic inorganic nitrate supplementation does not improve metabolic health and worsens disease progression in mice with diet-induced obesity.
Inorganic nitrate (NO3-) has been proposed to be of therapeutic use as a dietary supplement in obesity and related conditions including the Metabolic Syndrome (MetS), type-II diabetes and metabolic dysfunction associated steatotic liver disease (MASLD). Administration of NO3- to endothelial nitric o...
2025-07-14 | MTBLS9526 | MetaboLights
MetabolomicsIn Vitro 1H NMR Metabolic Profiles of Liver, Brain, and Serum in Rats After Chronic Consumption of Alcohol

The impact of alcohol on the body can be investigated with NMR spectroscopy in vitro, which can detect a wide range of metabolites but preparing samples includes tissue biopsy. Blood sampling is less invasive, but blood metabolic content might not reflect the changes occurring in other t...

2023-02-20 | MTBLS453 | MetaboLights
ProteomicsBlubber proteome response to repeated ACTH administration in juvenile elephant seals
Proteins were isolated from the inner blubber layer (closest to muscle) of juvenile elephant seals undergoing a repeated ACTH administration experiment (for details, see McCormley et al., 2018, doi: 10.1093/conphys/coy040; Deyarmin et al., 2019, doi:10.1038/s41598-019-39089-2). Sample preparation wa...
ORGANISM(S): Mirounga Angustirostris (ncbitaxon:9716) 
2019-07-29 | MSV000084153 | MassIVE
TranscriptomicsTranscription profiling of D34+ BCR-ABL+ cells of CML patients in chronic phase or blast crisis to identify differentially expressed stage-specific genes
Profiling CD34+ BCR-ABL+ cells of CML patients in chronic phase or blast crisis to identify differentially expressed stage-specific genes.
ORGANISM(S): Homo sapiens 
2006-08-08 | E-MEXP-480 | biostudies-arrayexpress
TranscriptomicsMicroRNA expression profiling predicts clinical outcome of chronic hepatitis C by interferon administration
We attempt to catalog the microRNA (miRNA) expression profile according to the response of combination therapy in order to predict the outcome of drug-response before administration and clarify the relationship between aberrant expression of miRNAs and chronic liver disease. We quantified expression...
ORGANISM(S): Homo sapiens 
2010-12-30 | E-GEOD-16922 | biostudies-arrayexpress
ProteomicsCharacterization of hyperglycemia due to sub-chronic administration of red ginseng extract via comparative global proteomic analysis
Ginseng (Panax ginseng Meyer) is commonly used as an herbal remedy worldwide. Few studies have explored the possible physiological changes in the liver although patients often self-medicate with ginseng preparations, which may lead to exceeding the recommended dose for long-term administration. Here...
ORGANISM(S): Mus musculus (Mouse) 
2021-09-10 | PXD023731 | Pride
Korean red ginseng  proteomics  cystathionin beta-synthase  cystathionine gamma- lyase  hydrogen sulfide 
ProteomicsProteomic analysis reveals the neurotoxic effects of chronic methamphetamine self-administration-induced cognitive impairments and the role of melatonin-enhanced restorative process during drug withdrawal.
, this study aimed to investigate the mechanisms underlying neuropathological processes related to cognitive impairment in mice chronically-treated with METH. In addition, the effective melatonin on recovery of neurological dysfunction and neurobehavioral deficits during METH withdrawal was also inv...
ORGANISM(S): Mus musculus (Mouse) 
2023-10-24 | PXD043828 | Pride
Mitophagy Cognitive function Methamphetamine Neurotoxicity Mitochondria Neuroplasticity Drug addiction Neurodegeneration Proteomics. Melatonin 
ProteomicsEffect of Chronic Methamphetamine Exposure on the Neuroproteomics of Rat Brain Tissues
Nowadays, drug abuse and addiction are serious public health problems in the USA. Methamphetamine (METH) is one of the most abused drugs, which is known to cause brain damage from repeated exposure on human. Herein, a proteomic study was applied to evaluate METH-induced brain protein dynamics follow...
ORGANISM(S): Rattus norvegicus (Rat) 
2016-04-21 | PXD000915 | Pride
Chronic administration Proteomics Escalating dose Neuroproteomics Systems biology Drug abuse Methamphetamine 
Sort   by:  
 Page size