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TranscriptomicsTranscription profiling of human lung adenocarcinoma A549 cells treated with vehicle (DMSO) or Etoposide (ETOP, 10 uM ), Benzo(a)pyrene Cryptolepineand 2-Amino-1-methyl-6-phenylimidazo [4,5-b]pyridine for 6 h, 16 h, 24 h, 48 h and 72 h
Title: Prediction of cell cycle behaviour in response to DNA damage agents via transcriptomic approach
Description: Human lung adenocarcinoma A549 cells were treated with vehicle (DMSO) or Etoposide (ETOP, 10 M-BM-5M ), Benzo(a)pyrene (BaP, 25 M-BM-5M ), Cryptolepine ( CLP, 2.5 M-BM-5M) and 2...
ORGANISM(S): Homo sapiens 
2006-06-01 | E-MIMR-102 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse H-2Kb muscle cells treated with metformin (2mM) or insulin (100nM) for 0, 2 or 12 hours
The basic design of the experiment is as described in Fryer et al.(2000)Diabetes 49:1978, and is similar to proto-BAIR (EXP_BAIR_0603_02). H-2Kb muscle cells were treated with metformin (2mM) or insulin (100nM) for 0, 2 or 12 hours.
ORGANISM(S): Mus musculus 
2022-11-23 | E-BAIR-7 | biostudies-arrayexpress
TranscriptomicsTranscription profiling time series of kidney, liver and spleen from three strains of mice infected with Trypanosoma congolense to investigate strain differences in susceptibility
In this experiment, mice from 3 strains A/J, Balb C and C57Bl6 were infected with Trypanosoma Congolense, IL1180 clone, African sleeping sickness, a disease which affects cattle in sub-saharan Africa. These mouse strains were chosen because they are a model for tolerance to infection in cattle, wi...
ORGANISM(S): Mus musculus 
2007-08-21 | E-MEXP-1190 | biostudies-arrayexpress
UnknownProbing neural codes with two-photon holographic optogenetics.
Not available
S-EPMC9793863 | biostudies-literature
UnknownA subset of octopaminergic neurons that promotes feeding initiation in Drosophila melanogaster.
Not available
S-EPMC6021039 | biostudies-literature
Proteomics- Identification of Gαi2-interacting proteins via affinity pull-down and quantitative mass-spectrometry analysis.
In studying patients with activating GNAI2 mutations, we observed T cell hyperresponsiveness that was independent of cAMP suppression. Therefore, we hypothesized that Gαi2 utilizes alternative signal transduction pathways which might be delineated by identifying its interacting proteins in T cells. ...
ORGANISM(S): Homo sapiens (Human) Escherichia coli 
2024-09-20 | PXD048980 | Pride
Gpcrs G-protein coupled receptors Gnai2 - gαi2 G-protein 
ProteomicsVagus Nerve Stimulation enhances remyelination and decreases innate neuroinflammation in a Multiple Sclerosis rodent model.
This study investigated the effect of Vagus Nerve Stimulation (VNS) on innate neuroinflammation and remyelination in lysolecithin (LPC) induced demyelination, a preclinical model for Multiple Sclerosis (MS). In a first experiment (demyelination experiment), LPC was injected in the corpus callosum of...
ORGANISM(S): Rattus norvegicus (Rat) 
2024-05-10 | PXD050858 | Pride
Vagus nerve stimulation (vns) Neuroinflammation Remyelination Synapses Multiple sclerosis (ms) Lc-ms/ms 
UnknownMolecular Epidemiology of SARS-CoV-2 in Diverse Environmental Samples Globally.
Not available
S-EPMC8401355 | biostudies-literature
UnknownFluorogenic rhodamine B derivatives that become brighter at neutral pH.
Not available
S-EPMC12704479 | biostudies-literature
TranscriptomicsCorrelation of transcriptomic responses and metal bioaccumulation in Mytilus edulis L. reveals early indicators of stress
Marine biomonitoring programs in the U.S. and Europe have historically relied on monitoring tissue concentrations of bivalves to monitor contaminant levels and ecosystem health. By integrating M-bM-^@M-^Xomic methods with these tissue residue approaches we can uncover mechanistic insight to help li...
ORGANISM(S): Mytilus edulis 
2014-06-20 | E-GEOD-58649 | biostudies-arrayexpress
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