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TranscriptomicsTranscription profiling by array of human T24 bladder cancer cells in response to hypericin-mediated photodynamic therapy in the absence or presence of the p38 MAPK inhibitor PD169316
Study of the gene expression of T24 bladder cancer cells in response to hypericin-mediated photodynamic therapy in the absence or presence of the p38 MAPK inhibitor PD169316
ORGANISM(S): Homo sapiens 
2007-10-01 | E-MEXP-1220 | biostudies-arrayexpress
TranscriptomicsA predictive and prognostic 38-gene expression signature for metastatic relapse in breast cancer
Background Currently, no gene-expression signature (GES) established from node-positive cohorts, able to predict breast cancer evolution after systemic adjuvant chemotherapy, exists. Methods Gene-expression profiles of 252 node-positive patients (median follow-up: 7.7 years), mostly included in a ra...
ORGANISM(S): Homo sapiens 
2008-11-27 | E-GEOD-11264 | biostudies-arrayexpress
UnknownHyponatremia is a marker of disease severity in HIV-infected patients: a retrospective cohort study.
Not available
S-EPMC5267411 | biostudies-literature
UnknownFeeding Essential Oils to Neonatal Holstein Dairy Calves Results in Increased Ruminal Prevotellaceae Abundance and Propionate Concentrations.
Not available
S-EPMC6560426 | biostudies-literature
ProteomicsWobble tRNA modification dependent protein aggregates modification
We want to assess the features of proteins whose aggregation depends on defects in traslation by the loss of the mcm5s2 modification on the urifdine in position 34 of some tRNAs.
ORGANISM(S): Homo sapiens (Human) 
2021-02-24 | PXD019590 | Pride
Trna modification Aggregates Elongator Cancer 
ProteomicsWobble tRNA modification dependent proteome
We want to assess the features of proteins whose translation depends on the mcm5s2 modification of urifdine in position 34 of some tRNAs.
ORGANISM(S): Homo sapiens (Human) 
2021-02-24 | PXD019620 | Pride
Trna modification Elongator Cancer 
TranscriptomicsHigh-resolution comparative genomic hybridization of inflammatory breast cancer and identification of candidate genes
Inflammatory breast cancer (IBC) is an aggressive form of BC poorly defined at the molecular level. We compared the molecular portraits of 63 IBC and 134 non-IBC (nIBC) clinical samples. Genomic imbalances of 49 IBCs and 124 nIBCs were determined using high-resolution array-comparative genomic hybri...
ORGANISM(S): Homo sapiens 
2011-03-01 | E-GEOD-23720 | biostudies-arrayexpress
ProteomicsLC-M/MS Protein aggregation isolation is murine melanoma lines after OSGEP depletion
The immune response in cancer, particularly in melanoma, is often hindered by tumour-induced immune evasion strategies, but the precise mechanisms for this remains unclear. Here, we reveal how the tRNA modification threonine-6-adenosine (t6A), mediated by O-sialoglycoprotein endopeptidase (OSGEP), m...
ORGANISM(S): Mus musculus (Mouse) 
2026-04-06 | PXD059835 | Pride
Trna modification Melanoma Protein misfolding 
TranscriptomicsAnalysis of the implication of the DBIRD complex (DBC1 and ZNF326/ZIRD) in gene expression and alternative splicing
Alternative mRNA splicing is the main reason vast mammalian proteomic complexity can be achieved with a limited number of genes. Splicing is physically and functionally coupled to transcription and the rate of transcript elongation has a profound effect on splicing. As the nascent pre-mRNA emerges f...
ORGANISM(S): Homo sapiens 
2012-03-20 | E-GEOD-35480 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human HeLa cells in response to IKAP/hELP1 siRNA transfection and/or tumor necrosis factor-a treatment
HeLa cells were un-transfected or transfected with specific siRNAs (20µM) targeting IKAP/hELP1 or non-specific siRNAs against GFP. Same experiment was done by stimulating the cells for 1 hour with TNF-a (200U/ml). conditions: 1/untransfected 2/siRNAs IKAP 3/untransfected + TNF-a 200U/ml 1h 4/siRNAs ...
ORGANISM(S): Homo sapiens 
2022-11-21 | E-MEXP-641 | biostudies-arrayexpress
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