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GenomicsPolII Rpb3 ChIP-seq data from D. melanogaster
We performed Pol II ChIP-seq experiments with 3rd instar larva salivary glands material from male, female and MSL2 RNAi D.melanogaster, as well as from S2 cell lines material. The antibody used recognizes the Rpb3 subunit of RNA Pol II irrespective of the phosphorylation state of the Rpb1 carboxy-te...
ORGANISM(S): Drosophila melanogaster 
2012-07-27 | E-MTAB-1112 | biostudies-arrayexpress
TranscriptomicsGene expression profiling of antigen-specific T cells upon CCR9 knockdown in MCF7 cells.
Tumor cells are known to express immune-inhibitory ligands on their surface to mediate resistance against cytotoxic T lymphocytes. Using a high-throughput RNAi screening assay, we identified CCR9 as a potent tumor-specific immune checkpoint molecule that inhibited T cell-mediated tumor lysis. To und...
ORGANISM(S): Homo sapiens 
2015-02-19 | E-MTAB-3244 | biostudies-arrayexpress
ProteomicsRBPome of primary mouse T helper cells
Post-transcriptional gene regulation is complex, dynamic and ensures proper T cell function. The targeted transcripts can simultaneously respond to various factors as evident for Icos, an mRNA regulated by several RNA binding proteins (RBPs), including Roquin. However, fundamental information about ...
ORGANISM(S): Mus musculus (Mouse) 
2021-07-01 | PXD022795 | Pride
Mouse Oops Rna binding proteins 
ProteomicsRBPome of primary human T helper cells
Post-transcriptional gene regulation is complex, dynamic and ensures proper T cell function. The targeted transcripts can simultaneously respond to various factors as evident for Icos, an mRNA regulated by several RNA binding proteins (RBPs), including Roquin. However, fundamental information about ...
ORGANISM(S): Homo sapiens (Human) 
2021-07-01 | PXD021164 | Pride
Human Rna interaction capture Rna binding proteins 
ProteomicsRBPome of primary human T helper cells
Post-transcriptional gene regulation is complex, dynamic and ensures proper T cell function. The targeted transcripts can simultaneously respond to various factors as evident for Icos, an mRNA regulated by several RNA binding proteins (RBPs), including Roquin. However, fundamental information about ...
ORGANISM(S): Homo sapiens (Human) 
2021-07-01 | PXD021169 | Pride
Human Oops Rna binding proteins 
ProteomicsRBPome of primary mouse T helper cells
Post-transcriptional gene regulation by mRNA-binding proteins (RBPs) ensures an important layer to control protein outcome. It includes many fundamental processes, ranging from splicing to transport, decay and translation. Although recent technical developments allow the identification of mRNA-bindi...
ORGANISM(S): Mus musculus (Mouse) 
2021-07-01 | PXD008830 | Pride
Rbp Mrna interactome capture Immune cells 
UnknownAn increasing number of states filled Conrad 30 waivers for recruiting international medical graduates.
Not available
S-EPMC11364145 | biostudies-literature
ProteomicsDefining the RBPome of T helper cells to study higher order post-transcriptional gene 1 regulation
Post-transcriptional gene regulation in T cells is dynamic and complex as targeted transcripts respond to various factors. This becomes evident for the Icos mRNA encoding an essential costimulatory receptorthatexhibits coordinate regulation by several RNA-binding proteins (RBPs), including Roquin-1 ...
ORGANISM(S): Mus musculus (Mouse) 
2021-06-28 | PXD026716 | Pride
Bio-id Roquin Rbpome 
UnknownFLT3-regulated antigens as targets for leukemia-reactive cytotoxic T lymphocytes.
Not available
S-EPMC3255276 | biostudies-literature
GenomicsMOF, H4 and H4K16ac ChIP-seq experiments in D.melanogaster
We generated MOF, H4 and H4K16ac ChIP-seq experiments in D.melanogaster male and female wt. All experiments were performed with 3rd instard salivary glands biological material. Raw and processed data are provided here.
ORGANISM(S): Drosophila melanogaster 
2012-02-08 | E-MTAB-911 | biostudies-arrayexpress
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