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ProteomicsTRAIP regulates DNA double-strand break-induced ATM activation
TRAIP is a functional E3 ubiquitin ligase with a RING finger domain at the N-terminal end. To find TRAIP partners and substrates we used a proximity-dependent biotinylation assay (Bio-ID) which can identify direct protein-protein interaction but also proteins building a complex without requiring di...
ORGANISM(S): Homo sapiens (Human) 
2024-05-07 | PXD006715 | Pride
Human cells Protein interactions Dna damage Orbitrap Proximity labelling Bioid Tandem ms 
ProteomicsCYRI-B loss promotes enlarged mature focal adhesions and restricts microtubule and ERC1 access to the cell leading edge
CYRI proteins promote lamellipodial dynamics by opposing Rac1-mediated activation of the Scar/WAVE complex. This activity also supports resolution of macropinocytic cups, promoting internalisation of surface proteins, including integrins. Here, we show that CYRI-B also promotes focal adhesion matu...
ORGANISM(S): Mus musculus (Mouse) 
2025-12-29 | PXD062975 | Pride
Vinculin Bio-id Integrins Actin cytoskeleton Erc1 Focal adhesions Paxillin Cyri-b Microtubules 
UnknownMolecular typing of West Nile Virus, Dengue, and St. Louis encephalitis using multiplex sequencing.
Not available
S-EPMC1867533 | biostudies-literature
UnknownSpeciation and Bio-Imaging of Chromium in Taraxacum officinale Using HPLC Post-column ID-ICP-MS, High Resolution MS and Laser Ablation ICP-MS Techniques.
Not available
S-EPMC9177994 | biostudies-literature
ProteomicsDefining the RBPome of T helper cells to study higher order post-transcriptional gene 1 regulation
Post-transcriptional gene regulation in T cells is dynamic and complex as targeted transcripts respond to various factors. This becomes evident for the Icos mRNA encoding an essential costimulatory receptorthatexhibits coordinate regulation by several RNA-binding proteins (RBPs), including Roquin-1 ...
ORGANISM(S): Mus musculus (Mouse) 
2021-06-28 | PXD026716 | Pride
Bio-id Roquin Rbpome 
UnknownA European inter-laboratory trial to evaluate the performance of three serological methods for diagnosis of Mycoplasma bovis infection in cattle using latent class analysis.
Not available
S-EPMC6814985 | biostudies-literature
UnknownIdentification of epigenetic interactions between microRNA and DNA methylation associated with polycystic ovarian syndrome.
Not available
S-EPMC7782128 | biostudies-literature
UnknownAberrant miRNA-mRNA regulatory network in polycystic ovary syndrome is associated with markers of insulin sensitivity and inflammation.
Not available
S-EPMC8506717 | biostudies-literature
UnknownMonocytic THP-1 cells diverge significantly from their primary counterparts: a comparative examination of the chromosomal conformations and transcriptomes.
Not available
S-EPMC8569982 | biostudies-literature
UnknownThe non-coding RNA composition of the mitotic chromosome by 5'-tag sequencing.
Not available
S-EPMC4889943 | biostudies-literature
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