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TranscriptomicsTransposable elements and small RNAs contribute to gene expression divergence between Arabidopsis thaliana and Arabidopsis lyrata
This SuperSeries is composed of the following subset Series: GSE24571: Transposable elements and small RNAs contribute to gene expression divergence between Arabidopsis thaliana and Arabidopsis lyrata [RNA-Seq] GSE38109: Natural variation in Arabidopsis thaliana transcriptomes Refer to individual Se...
ORGANISM(S): Arabidopsis thaliana 
2012-05-21 | E-GEOD-38113 | biostudies-arrayexpress
ProteomicsUncovering deeply conserved motif combinations in rapidly evolving noncoding sequences
Here we focus on identifying conserved elements that are required for Chaserr function, a lncRNA that we recently characterized as being essential for mouse viability (https://doi.org/10.1038/s41467-019-13075-8). Chaserr is highly conserved in different species, and is located in close proximity (<2...
ORGANISM(S): Mus musculus (Mouse) 
2021-01-18 | PXD023093 | Pride
Conserved elements Chaserr Lncloom Lncrnas Dhx36 
GenomicsDifferential contribution of cis-regulatory elements to higher order chromatin structure and expression of the CFTR locus
Higher order chromatin structure establishes domains that organize the genome and coordinate gene expression. However, the molecular mechanisms controlling transcription of individual loci within a topological domain (TAD) are not fully understood. The cystic fibrosis transmembrane conductance reg...
ORGANISM(S): Homo sapiens 
2016-01-07 | E-GEOD-74709 | biostudies-arrayexpress
TranscriptomicsEnvironment-responsive transcription factors bind proto-silencer elements and regulate subtelomeric silencing
Subtelomeric chromatin is subject to evolutionarily conserved complex epigenetic regulation and is implicated in numerous aspects of cellular function including formation of heterochromatin, regulation of different stress response pathways, and control of lifespan. Subtelomeric DNA is characterized...
ORGANISM(S): Saccharomyces cerevisiae 
2011-05-02 | E-GEOD-21852 | biostudies-arrayexpress
GenomicsEffect of deleting ultra-conserved elements PAX6_Tarzan, PBX3_Claudia on gene expression in K562 cells
Effect of deleting ultra-conserved elements PAX6_Tarzan, PBX3_Claudia on gene expression in K562 cells
PRJNA1036670 | ENA
TranscriptomicsAn epigenetic mark of polycomb response elements implemented by Trx/MLL/COMPASS
In Drosophila, Polycomb Response Elements (PREs) are identified as genomic sequences allowing the maintenance of transcriptional repression in the absence of the initiating signal. Although PREs in Drosophila are well characterized, the existence of mammalian PRE-like elements remains debated. Accu...
ORGANISM(S): Homo sapiens 
2016-07-26 | E-GEOD-81795 | biostudies-arrayexpress
GenomicsIdentification of conserved cis-regulatory elements impact Mecp2 level and neurological functions
Identification of conserved cis-regulatory elements impact Mecp2 level and neurological functions
PRJNA640181 | ENA
GenomicsChIP-seq of ERG-bound regulatory elements in human and bovine vascular endothelial cells
In this study we set out to discover conserved orthologous ERG-bound gene regulatory elements in primary vascular endothelial cells isolated from human and cow
ORGANISM(S): Homo sapiens 
2017-06-15 | E-MTAB-5148 | biostudies-arrayexpress
TranscriptomicsSystematic identification of regulatory elements in conserved 3’-untranslated regions of human transcripts
We present a combined experimental/computational technology to reveal a catalogue of functional regulatory elements embedded in 3’UTRs of human transcripts. We used a bidirectional reporter system coupled with flow cytometry and high-throughput sequencing to measure the effect of short, non-coding v...
ORGANISM(S): Homo sapiens 
2014-03-21 | E-GEOD-55396 | biostudies-arrayexpress
UnknownExtensive Loss and Gain of Conserved Noncoding Elements During Early Teleost Evolution.
Not available
S-EPMC11034925 | biostudies-literature
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