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UnknownChemoprevention of colon and small intestinal tumorigenesis in APC(Min/+) mice by licofelone, a novel dual 5-LOX/COX inhibitor: potential implications for human colon cancer prevention.
Not available
S-EPMC3232346 | biostudies-literature
ProteomicsNuclear RNA forms an interconnected network of transcription-dependent and tunable microgels
The human cell nucleus is comprised of proteins, chromatin and RNA, yet how they interact to form supramolecular structures and drive key biological processes remains unknown. Conflicting models have proposed either a fluid-like or solid-like nature for the intranuclear microenvironment. To reconcil...
ORGANISM(S): Homo sapiens (Human) 
2024-06-18 | PXD053208 | Pride
Nuclear architecture Chromatin Transcription Hnrnpu Xrn2 Saf-a Rna Microphase separation Bridging-induced attraction 
ProteomicsPARP1-dependent DNA-protein crosslink repair
DNA-protein crosslinks (DPCs) are toxic lesions that inhibit DNA related processes. Post-translational modifications (PTMs), including SUMOylation and ubiquitylation, play a central role in DPC resolution, but whether other PTMs are also involved remains elusive. Here, we identify a DPC repair pathw...
ORGANISM(S): Xenopus laevis (African clawed frog) 
2024-08-06 | PXD043107 | Pride
Xenopus Parp1 Top1 Dna-protein crosslink Adp-ribosylation Ddi2 Dna damage Ubiquitin Sumo P97 
UnknownPrognostic Potential of the Baseline Pan-Immune-Inflammation Value and Neutrophil/Lymphocyte Ratio in Stage I to III Melanoma Patients.
Not available
S-EPMC9496745 | biostudies-literature
UnknownEarly-stage immunoexpression of inflammatory, angiogenic, and survival markers in tongue epithelium of mice exposed to hookah smoke.
Not available
S-EPMC11864539 | biostudies-literature
UnknownPiperlongumine restores the balance of autophagy and apoptosis by increasing BCL2 phosphorylation in rotenone-induced Parkinson disease models.
Not available
S-EPMC6070010 | biostudies-literature
UnknownEicosapentaenoic acid attenuates renal lipotoxicity by restoring autophagic flux.
Not available
S-EPMC8354598 | biostudies-literature
TranscriptomicsChemical map of S. pombe reveals species-specific features in nucleosome positioning
Knowing the exact positions of nucleosomes not only advances our understanding of their role in gene regulation, but also the mechanisms that underlie between-species variation in chromatin structure. We have generated a chemical map of nucleosomes in vivo in Schizosaccharomyces pombe at base pair r...
ORGANISM(S): Schizosaccharomyces pombe 
2013-11-12 | E-GEOD-46975 | biostudies-arrayexpress
GenomicsCancer Genetic Markers of Susceptibility (CGEMS) Breast Cancer Genome-Wide Association Study (GWAS) - Primary Scan (Stage 1) - Nurses' Health Study

The Cancer Genetic Markers of Susceptibility (CGEMS) breast cancer genome-wide association study (GWAS) included genotyping 528,173 SNPs (Illumina HumanHap550) in 1,145 postmenopausal women of European ancestry with invasive breast cancer and 1,142 controls from the Nurses' Health Study (...

phs000147.v1.p1 | EGA
UnknownEvaluation of human papillomavirus antibodies and risk of subsequent head and neck cancer.
Not available
S-EPMC3709056 | biostudies-literature
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