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GenomicsHomo sapiens
CRISPaint
PRJNA276500 | ENA
UnknownCRISPaint allows modular base-specific gene tagging using a ligase-4-dependent mechanism.
Not available
S-EPMC4974478 | biostudies-literature
UnknownEfficient and rapid fluorescent protein knock-in with universal donors in mouse embryonic stem cells.
Not available
S-EPMC10233722 | biostudies-literature
UnknownGene Knock-Ins in Drosophila Using Homology-Independent Insertion of Universal Donor Plasmids.
Not available
S-EPMC6944404 | biostudies-literature
Proteomicsct of PROTAC #89, which targets an endogenously SNAP-tagged clathrin light chain, on the HAP1 cell proteome
We would like to investigate what effect degradation of the clathrin light chain has on the HAP1 proteome. We therefore tagged the clathrin light chain (CLC) in HAP1 cells endogenously with a SNAP-tag via CRISPaint. The degradation of the SNAP-tagged protein is induced by the addition of a SNAP-PROT...
ORGANISM(S): Homo sapiens (Human) 
2025-05-06 | PXD049283 | Pride
Protac Clathrin Hap1 
UnknownC-terminal tagging impairs AGO2 function.
Not available
S-EPMC12296108 | biostudies-literature
ProteomicsGFI1B and LSD1 repress myeloid traits during megakaryocyte differentiation
The transcription factor Growth Factor Independence 1B (GFI1B) recruits Lysine Specific Demethylase 1A (LSD1/KDM1A) to stimulate gene programs relevant for megakaryocyte and platelet biology. Inherited pathogenic GFI1B variants result in thrombocytopenia and bleeding propensities with varying intens...
ORGANISM(S): Homo sapiens (Human) 
2024-03-28 | PXD050401 | Pride
Human Kdm1a Crispaint Gfi1b 
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