Sort   by:  
 Page size 
ProteomicsPhosphoproteomics of mouse cardiomyocytes reveals signalling pathways triggered by a vasodilator cryptide
Animal venoms are natural sources of bioactive molecules such as cryptides that consist in biological active peptides released after proteolytic cleavage of a peptide or protein precursor. The KPP is a cryptided derived from the c-terminal of an hypotensin (TsHpI) a peptide isolated from the venom o...
ORGANISM(S): Mus musculus (Mouse) 
2020-07-06 | PXD015068 | Pride
Hipotensins Venome Scorpion Cryptide Cardiomyocytes Phosphopreteomics 
ProteomicsLachesis muta snake venom peptidome
Snake venoms are known to be major sources of peptides with different pharmacological properties. In this study, we comprehensively explored the venom peptidomes of three specimens of Lachesis muta, the largest venomous snake in South America, using mass spectrometry techniques. The analysis reveale...
ORGANISM(S): Lachesis muta 
2023-10-23 | PXD045732 | Pride
Peptidomics Bradykinin potentiating peptides Mass spectrometry Lachesis muta Snake venom Snake venom metalloproteinases 
UnknownQuantity - but not diversity - of secreted peptides and proteins increases with age in the tree frog Pithecopus nordestinus.
Not available
S-EPMC8020714 | biostudies-literature
TranscriptomicsAbalone peptide increases stress resilience and cost-free longevity via SKN-1-governed transcriptional metabolic reprogramming in C. elegans
A major goal of healthy aging is to prevent declining resilience and increasing frailty, which are associated with many chronic diseases and deterioration of stress response. We have successfully used loss-or-gain model of stress survival to quantify organismal resilience. As a proof of concept, thi...
ORGANISM(S): Caenorhabditis elegans 
2023-11-06 | GSE246759 | GEO
UnknownAbalone peptide increases stress resilience and cost-free longevity via SKN-1-governed transcriptional metabolic reprogramming in C. elegans.
Not available
S-EPMC10861207 | biostudies-literature
ProteomicsA novel peptide from Bothrops cotiara peptidome
The knowledge regarding toxins diversity, composition, structure, molecular and pharmacological interactions involved in the process of envenomation provide lessons for drug design based on these natural molecular scaffolds and pharmacophores of toxins. This study unravels new toxins sequenced by ma...
ORGANISM(S): Bothrops cotiara 
2023-10-20 | PXD041473 | Pride
Bothrops cotiara Peptidome. 
ProteomicsPeptidome of Bothrops cotiara snake venom
The knowledge regarding toxins diversity, composition, structure, molecular and pharmacological interactions involved in the process of envenomation provide lessons for drug design based on these natural molecular scaffolds and pharmacophores of toxins. This study unravels new toxins sequenced by ma...
ORGANISM(S): Bothrops cotiara 
2023-10-20 | PXD036130 | Pride
Bothrops cotiara Peptidome Snake venoms 
GenomicsAbalone peptide increases stress resilience and cost-free longevity via SKN-1-governed transcriptional metabolic reprogramming in C. elegans
Abalone peptide increases stress resilience and cost-free longevity via SKN-1-governed transcriptional metabolic reprogramming in C. elegans
PRJNA1034565 | ENA
Sort   by:  
 Page size