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ProteomicsThe molecular appearance of native TRPM7 channel complexes identified by high-resolution proteomics
The transient receptor potential cation channel, subfamily M, member 7 (TRPM7) is a ubiquitously expressed membrane protein consisting of an ion channel domain and an intracellularly located protein kinase domain. TRPM7 plays a fundamental role in the cellular uptake of divalent cations such as Zn2+...
ORGANISM(S): Mus musculus (Mouse) Homo sapiens (Human) Rattus norvegicus (Rat) 
2021-11-29 | PXD025279 | Pride
Ap-ms Lc-ms Csbn-ms Magnesium Cnnm Calcium Trpm7 Arl15 Zinc 
UnknownCryo-slicing Blue Native-Mass Spectrometry (csBN-MS), a Novel Technology for High Resolution Complexome Profiling.
Not available
S-EPMC4739680 | biostudies-literature
ProteomicsCryo-slicing BN-MS of rat brain mitochondrial proteins
Blue-native gel electrophoresis (BN) is a powerful method for protein separation. Combined with liquid chromatography-tandem mass spectrometry (LC-MS/MS) it enables large-scale identification of protein complexes and their subunits. Current BN-MS approaches, however, are limited in size resolution, ...
ORGANISM(S): Rattus norvegicus (Rat) 
2015-12-01 | PXD002681 | Pride
Cryo-slicing bn-ms lc-ms/ms complexome proteine profiles 
ProteomicsA stop-and-go mechanism controls mitochondrial respiration
Oxidative phosphorylation (OXPHOS) is essential for the synthesis of the vast majority of ATP in eukaryotic cells. It is carried out by multi-protein assemblies that form the electron transport chain (ETC), which are coupled to the mitochondrial ATP synthase, which uses the proton gradient generated...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2024-02-16 | PXD044800 | Pride
Protein complex assembly Mitochondria Complex stoichiometry Mitoribosome Respiratory chain 
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