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ProteomicsCross-Linking Mass Spectrometry (CXMS) of human pre-60S ribosomal particles
Cross-Linking Mass Spectrometry (CXMS) analysis of human pre-60S ribosomal particles.
ORGANISM(S): Homo Sapiens 
2020-05-07 | PXD019025 |
ProteomicsMolecular mechanisms of recruitment, function and regulation of the RNA helicase UPF1 in replication-dependent histone mRNA decay
Metazoan histone mRNAs are a unique class of mRNAs that lack the poly(A) tail present in all other eukaryotic transcripts. Instead, they end in a conserved stem-loop (SL) structure, necessitating a decay mechanism that is distinct from deadenylation-initiated degradation. Here, combining cryoEM with...
ORGANISM(S): Homo sapiens (Human) 
2025-12-08 | PXD070077 | Pride
Exoribonuclease 3’hexo Cxms Rna helicase upf1 Cryoem Histone mrna decay Slbp 
ProteomicsSubcellular Interactomes Revealed by Merging APEX with Cross-linking Mass Spectrometry
An integrating APEX proximity labeling and chemical cross-linking coupled with mass spectrometry (CXMS) platform named APEX-CXMS for spatially resolved subcellular interactome profiling in a high-throughput ma
ORGANISM(S): Homo Sapiens 
2022-07-21 | PXD033838 |
ProteomicspLink 2: A high-speed search engine with systematic evaluation for proteome-scale identification of cross-linked peptides
Crosslinking mass spectrometry (CXMS) is a powerful technique to study protein structures and interactions. However, software tools for CXMS data analysis suffer from poor speed and credibility, especially at a proteome scale. Here, we introduce pLink 2, a search engine with higher speed and credibi...
ORGANISM(S): Escherichia coli 
2019-07-26 | PXD012109 | Pride
E.coli Qehf 
ProteomicsCXMS BS3 Ras/BRAF/MEK/1433 complex
RAF-family kinases are activated by recruitment to the plasma membrane by GTP-bound RAS, where they initiate signaling through the MAP kinase cascade. Here we crosslinked (BS3), digested (trypsin), and analyzed via LC-MS/MS KRAS (human, residues 1-169) bound to intact BRAF (human) in an autoinhibit...
ORGANISM(S): Spodoptera frugiperda Homo sapiens (Human) 
2023-10-24 | PXD042584 | Pride
Cxms Human Braf Mek1 14-3-3 Sf9 Kras 
ProteomicsCrosslinking Mapping of yeast Komagataella phaffii TFIID complex
Transcription preinitiation complex assembly on the promoters of protein encoding genes is nucleated in vivo by TFIID composed of the TATA-box Binding Protein (TBP) and 13 TBP-associate factors (Tafs) providing regulatory and chromatin binding functions. We used CXMS to study the organization and st...
ORGANISM(S): Komagataella phaffii 
2018-10-08 | PXD011092 | Pride
K. phaffii tfiid cxms bs3 
UnknownImproving mass spectrometry analysis of protein structures with arginine-selective chemical cross-linkers.
Not available
S-EPMC6718413 | biostudies-literature
ProteomicsA Glycosidic-Bond-Based Mass-Spectrometry-Cleavable Cross-linker Enables In Vivo Cross-linking for Protein Complex Analysis
Chemical cross-linking mass spectrometry (CXMS) has emerged as a powerful technology to analyze protein complex structure and interaction. However, the spectral fragmentation behavior and spectral data retrieval of cross-linked peptides are more complex than single peptides. In this study, we design...
ORGANISM(S): Homo Sapiens Saccharomyces Cerevisiae 
2023-12-06 | PXD047554 |
UnknownComMap: a software to perform large-scale structure-based mapping for cross-linking mass spectrometry.
Not available
S-EPMC9960907 | biostudies-literature
ProteomicsYeast SWI/SNF complex - Loss of Snf5 Induces Formation of an Aberrant SWI/SNF Complex
This project uses crosslinked based mass spectrometry (CXMS) to study the architecture of yeast SWI/SNF complex.
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2018-06-14 | PXD005948 | Pride
Swi/snf bs3 crosslinking architecture 
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