Cyclic ion mobility

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Cyclic ion mobility for hydrogen/deuterium exchange-mass spectrometry applications

Hydrogen/deuterium exchange-mass spectrometry (HDX-MS) has emerged as a powerful tool to probe protein dynamics. As a bottom-up technique, HDX-MS provides information at peptide-level resolution, allowing structural localisation of dynamic changes. Consequently, HDX-MS data quality is largely determ...

ORGANISM(S): Homo sapiens (Human) Escherichia coli

2024-04-08 | PXD048293 | Pride

Characterization of Sugammadex-Related Isomeric Cyclodextrin Impurities Using Cyclic Ion Mobility High-Resolution Mass Spectrometry.

Not available

S-EPMC11808773 | biostudies-literature

Optimum collision energies for proteomics: The impact of ion mobility separation

We performed LC-MS/MS measurements on a Waters Select Series Cyclic IMS QTof mass spectrometer with varied CE settings both with and without IMS. We investigated the CE dependence of identification score, using Byonic search engine, for more than 1000 tryptic peptides from HeLa digest standard. We d...

ORGANISM(S): Homo Sapiens (ncbitaxon:9606)

2022-12-20 | MSV000090944 | MassIVE

LESA Cyclic Ion Mobility Mass Spectrometry of Intact Proteins from Thin Tissue Sections.

Not available

S-EPMC7304663 | biostudies-literature

Accurate Collisional Cross Section Measurement by Multipass Cyclic Ion Mobility Spectrometry.

Not available

S-EPMC11682735 | biostudies-literature

Exploring Top-Down Mass Spectrometric Approaches To Probe Forest Cobra (Naja melanoleuca) Venom Proteoforms

Three main top-down mass spectrometry methodologies were employed in a proof-of-concept study to characterise selected three finger toxins and phospholipase A2 toxins from the forest cobra (Naja melanoleuca) venom. The novel utility of data-independent acquisition, alternative hybrid ECD-CID fragmen...

ORGANISM(S): Naja melanoleuca

2024-09-05 | PXD052561 | Pride

Ecd-cid fragmentation Proteoforms Top-down proteomics Cyclic ion mobility Snake venom Data-independent acquisition

Surface-induced dissociation of protein complexes on a cyclic ion mobility spectrometer.

Not available

S-EPMC8574189 | biostudies-literature

Spatial Ion Compression without Loss of Resolution on a Cyclic Ion Mobility Spectrometry-Mass Spectrometry Platform.

Not available

S-EPMC12768463 | biostudies-literature

MultiPassMerger: Automated data processing for multipass cyclic ion mobility HDX-MS.

Not available

S-EPMC12102732 | biostudies-literature