Pre-infection with Toxoplasma parasites inhibits induction of an interferon gamma responsive gene expression program. In this study we aimed to determine what role host negative regulatory proteins that are induced by Toxoplasma infection, such as SOCS-1, have in this inhibition. We used Affymetrix ...
Pre-infection with Toxoplasma parasites inhibits induction of an interferon gamma responsive gene expression program. In this study we aimed to determine what role host negative regulatory proteins that are induced by Toxoplasma infection, such as SOCS-1, have in this inhibition. We used Affymetrix...
Elevated levels of androgen receptor (AR) in prostate cancer confer resistance to current antiandrogens and play a causal role in disease progression due to persistent target gene activation. Through pharmacologic and genetic approaches, we show that half of all direct AR target genes, including TM...
Elevated levels of androgen receptor (AR) in prostate cancer confer resistance to current antiandrogens and play a causal role in disease progression due to persistent target gene activation. Through pharmacologic and genetic approaches, we show that half of all direct AR target genes, including TM...
Expression data from cyclohexamide treated Human Foreskin Fibroblasts (HFFs) infected with type I Toxoplasma gondii and stimulated with interferon gamma.
E. coli lipopolysacharide was treated on SL2* cells for 1hr, 4 and 12hrs respectivly. cDNA from those cells was compared with control. For one sample, cyclohexamide was treated for 1hr and then LPS was treated for 4hrs. Then, compared with control.
The small intestine is a rapidly proliferating organ that is maintained by a small population of Lgr5-expressing intestinal stem cells (ISCs). However, several Lgr5-negative ISC populations have been identified, and this remarkable plasticity allows the intestine to rapidly respond to both the local...
Analysis of global variability of translation between the Eif6 WT control genotype and the Eif6 S235A mutated MEF lines. Ribosome Protected Fragments (RPFs) were obtained followwing the procedure reported in McGlincy NJ & Ingolia NT. Methods. 2017 (doi: 10.1016/j.ymeth.2017.05.028).
