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Helminth parasites secrete extracellular vesicles (EVs) as a means of exporting effector molecules into the host microenvironment. Once released, the parasite-derived EVs are internalised by host immune cells and trigger a range of biological effects including modulation of host immunity. While the ...
ORGANISM(S): Fasciola hepatica (Liver fluke) 
2019-11-12 | PXD007782 | Pride
Coenzyme A is an important cellular metabolite critical for metabolic processes and the regulation of gene expression. The recent discovery of its antioxidant role has highlighted its protective function that leads to the formation of a mixed-disulfide bond with protein cysteines, termed protein CoA...
ORGANISM(S): Bacillus subtilis subsp. subtilis str. L170 
2023-05-10 | PXD041347 | Pride
Background: The active site of matrix metalloproteinases (MMPs) is highly conserved, complicating the rational design of specific substrates and inhibitors for individual family members. Results: Active site specificity profiles of 9 MMPs were determined using high throughput Proteomic Identificatio...
ORGANISM(S): Homo sapiens (Human) 
2015-09-29 | PXD002265 | Pride
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