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The endosomal-lysosomal network is a hub of organelles that orchestrate the dynamic sorting of hundreds of integral membrane proteins to maintain cellular homeostasis. VPS29 is a central conductor of this network through its assembly into Retromer, Retriever and Commander endosomal sorting complexes...
ORGANISM(S): Homo sapiens (Human) 
2025-07-21 | PXD064959 | Pride
Retromer controls cellular homeostasis through regulating integral membrane protein sorting and transport and by controlling late-stage maturation of the endo-lysosomal network. Retromer dysfunction, which is linked to neurodegenerative disorders including Parkinson’s and Alzheimer’s diseases, manif...
ORGANISM(S): Homo sapiens (Human) 
2023-07-20 | PXD041323 | Pride
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