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The project aimed to identify interaction sites of RNF168 with the Nucleosomes. RNF168 interaction with the Nucleosome was probed by BS3 crosslinking to support structure modeling based on NMR and mutagenesis experiments
ORGANISM(S): Homo sapiens (Human) 
2019-04-02 | PXD012723 | Pride
Polycomb repressive complex-2 (PRC2) is a histone methyltransferase required for epigenetic silencing during development and cancer. Long non-coding RNAs (lncRNAs) recruit PRC2 to chromatin, but the general role of RNA in maintaining repressed chromatin is unknown. ChIP-seq, combined with RNA-seq, i...
ORGANISM(S): Homo sapiens 
XL-MS to identify interaction sites of PRC1-CBX8 with chromatin
ORGANISM(S): Homo sapiens (Human) 
2024-12-30 | PXD039589 | Pride
Recombinant PRC1 complex consisting of RNF2, PCGF4 and CBX8 was crosslinked with BS3 to identify complex structure
ORGANISM(S): Homo sapiens (Human) 
2024-12-30 | PXD049094 | Pride
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