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UnknownGlycopeptide database search and de novo sequencing with PEAKS GlycanFinder enable highly sensitive glycoproteomics.
Not available
S-EPMC10329677 | biostudies-literature
ProteomicsDirect mass spectrometry-based detection and antibody sequencing of Monoclonal Gammopathy of Undetermined Significance from patient serum
Monoclonal gammopathy of undetermined significance (MGUS) is a plasma cell disorder, leading to the presence of monoclonal antibody (i.e., M-protein) in serum, without clinical symptoms. Here we present a case study in which we detect MGUS by liquid-chromatography coupled with mass spectrometry (LC-...
ORGANISM(S): Homo sapiens (Human) 
2023-09-14 | PXD042266 | Pride
Antibody Glycoproteomics M-protein De novo 
UnknownNew glycoproteomics software, GlycoPep Evaluator, generates decoy glycopeptides de novo and enables accurate false discovery rate analysis for small data sets.
Not available
S-EPMC4165450 | biostudies-literature
UnknownExploring COVID-19 pathogenesis on command-line: A bioinformatics pipeline for handling and integrating omics data.
Not available
S-EPMC9095070 | biostudies-literature
ProteomicsInfluenza A virus- integrated glycomics, proteomics and glycoproteomics
This study describes how site-specific glycosylation of Influenza A virus changes in response to pressures from the host immune system, thereby allowing the virus to evolve and escape neutralization. We compared the glycosylation patterns of different virus strains as they evolve and correlated this...
ORGANISM(S): Orthomyxoviridae Homo sapiens (Human) 
2016-04-26 | PXD003498 | Pride
Influenza Lc-ms/ms Glycomics Glycoproteomics Hemagglutinin 
UnknownUncovering missing glycans and unexpected fragments with pGlycoNovo for site-specific glycosylation analysis across species.
Not available
S-EPMC11401942 | biostudies-literature
UnknownProteomic analysis of hydrogen peroxide-treated human chondrocytes shows endoplasmic reticulum stress, cytoskeleton remodeling, and altered secretome composition.
Not available
S-EPMC12166578 | biostudies-literature
ProteomicsRevisiting the effect of trypsin digestion buffers on artificial deamidation
Deamidation of asparagine and glutamine residues occurs spontaneously, accelerated by adjacent amino acid residues and influenced by pH, temperature, and incubation time. Standard proteolytic digestion induces significant deamidation, which is especially problematic in bottom-up proteomic studies. T...
ORGANISM(S): Mus musculus (Mouse) 
2025-03-11 | PXD054603 | Pride
De-glycopeptides Chemical deamidation De-glycoproteomics 
UnknownN-GlycositeAtlas: a database resource for mass spectrometry-based human N-linked glycoprotein and glycosylation site mapping.
Not available
S-EPMC6731604 | biostudies-literature
ProteomicsGlycoproteomics of Human and Mouse Brains in Alzheimer’s Disease
This study profiles glycoproteomic changes in human frontal cortex and mouse brain in Alzheimer’s disease models. We compare cognitively normal and AD human brain tissue, and wild-type and 5xFAD mouse brain, to define whether AD-associated hyperglycosylation reflects increased glycosylation of exist...
ORGANISM(S): Homo sapiens (Human) 
2026-03-31 | PXD075438 | Pride
Alzheimer’s disease  glycoproteomics  n-glycosylation  human brain  mouse brain 
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