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ProteomicsSpecific inhibition of splicing factor activity by decoy RNA oligonucleotides
Alternative splicing, a fundamental step in gene expression, is deregulated in many diseases. Splicing factors (SFs), which regulate this process, are up- or down regulated or mutated in several diseases including cancer. To date, there are no inhibitors that directly inhibit the activity of SFs. We...
ORGANISM(S): Homo sapiens (Human) 
2019-01-31 | PXD012564 | Pride
Splicing factors Alternative splicing Rbfox2 Ptbp1 Cancer Lc-ms Srsf1 Decoy oligonucleotides 
GenomicsSpecific inhibition of splicing factor activity by decoy RNA oligonucleotides
Specific inhibition of splicing factor activity by decoy RNA oligonucleotides
PRJNA522237 | ENA
TranscriptomicsSpecific inhibition of splicing factor activity by decoy RNA oligonucleotides
Alternative splicing, a fundamental step in gene expression, is deregulated in many diseases. Splicing factors (SFs), which regulate this process, are up- or down regulated or mutated in several diseases including cancer. To date, there are no inhibitors that directly inhibit the activity of SFs. We...
ORGANISM(S): Homo sapiens 
2019-02-14 | GSE126503 | GEO
UnknownSpecific inhibition of splicing factor activity by decoy RNA oligonucleotides.
Not available
S-EPMC6453957 | biostudies-literature
UnknownManipulating and understanding antibiotic production in Streptomyces coelicolor A3(2) with decoy oligonucleotides.
Not available
S-EPMC2242687 | biostudies-literature
ProteomicsStereo-random Oligonucleotides Enable Efficient Recruitment of ADAR in vitro and in vivo
We used our previously published isASO-ID protocol to identify binders for two different adenosine deaminases acting on RNA- (ADAR-) recruiting antisense oligonucleotides (ONs). The ONs differed in their phosphorothioate content and their RNA editing potency and efficiency through the recruitment of...
ORGANISM(S): Homo sapiens (Human) 
2025-07-31 | PXD066763 | Pride
Antisense oligonucleotide Basu Drug protein interactome Rna editing Proximity biotinylation Biotin ligase Silac In situ biotinylation Adar-recruiting oligonucleotides 
UnknownNucleic Acid Targeted Therapy: G4 Oligonucleotides Downregulate HRAS in Bladder Cancer Cells through a Decoy Mechanism.
Not available
S-EPMC4677363 | biostudies-literature
GenomicsHomo sapiens
Expression consequences of decoy vs scrambled oligonucleotides harboring AAAA[AGT]TT motif in MBA-MD-231 cell line
PRJNA123851 | ENA
TranscriptomicsTranscription profiling of human differentiated vs. undifferentiated SH-SY5Y cells transfected with a MeCP2 (transcriptional repressor) decoy to investigate the neurodevelopmental disorder Rett syndrome
Rett syndrome (RTT) is an X-linked dominant neurodevelopmental disorder caused by mutations in MECP2, encoding methyl-CpG-binding protein 2. MeCP2 is a transcriptional repressor elevated in mature neurons and is predicted to be required for neuronal maturation by regulating multiple target genes. Id...
ORGANISM(S): Homo sapiens 
2007-10-26 | E-GEOD-4600 | biostudies-arrayexpress
UnknownSubcellular localization as a limiting factor for utilization of decoy oligonucleotides.
Not available
S-EPMC528816 | biostudies-literature
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