Sort   by:  
 Page size 
ProteomicsData-driven rescoring meets identification transfer in multi-batch isobaric labeling experiments: the best of both worlds (ProSIMSIt)
Multi-batch isobaric labeling experiments are frequently applied for clinical and pharmaceutical studies of large sample cohorts. To tackle the critical issue of missing values in such studies, we introduce the ProSIMSIt pipeline. It combines the advantages of tandem mass spectrum clustering via SIM...
ORGANISM(S): Homo sapiens (Human) 
2025-05-07 | PXD057211 | Pride
Prediction Missing values Isobaric labelling Simsi-transfer Oktoberfest Maxquant 
ProteomicsDecrypting drug actions and protein modifications by dose- and time-resolved chemical proteomics
Measuring dose-dependent effects of drugs on post-translational modifications on a proteome-wide scale reveals how these drugs work in cells. Here, we present a quantitative chemical proteomic approach termed decryptM, able to assess target and pathway engagement as well as the mode of action (MoA)...
ORGANISM(S): Homo sapiens (Human) 
2023-03-17 | PXD037285 | Pride
Kat Screen Drug mode of action Post-translational modifciation Time-resolved Inhibitors Decryptm Proteome-wide Hdac Dose-resolved Kinase 
UnknownDecrypting the potency of anti-cancer therapeutics by using mass spectrometry to quantify post-translational modifications.
Not available
S-EPMC10261922 | biostudies-literature
UnknownDecrypting drug actions and protein modifications by dose- and time-resolved proteomics.
Not available
S-EPMC7615311 | biostudies-literature
UnknownProSIMSIt: The Best of Both Worlds in Data-Driven Rescoring and Identification Transfer.
Not available
S-EPMC11976853 | biostudies-literature
Sort   by:  
 Page size