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MetabolomicsMetabolomic and physiological analysis of bud differentiation in dense apple (Malus × domestica Borkh.) orchards following thinning and reshaping

BACKGROUND: In China, a majority of apple orchards were initially planted under arboriculture. Noteworthy, as the trees age, there is an increase in the number of branches and the degree of orchard depression and deterioration of the canopy light conditions. This phenomenon results in in blockage...

2025-01-20 | MTBLS11951 | MetaboLights
TranscriptomicsExpression data from Arabidopsis petioles in early stage dense canopy
Growth in dense stands induces shade avoidance responses. Early responses to neighbors seem to be assoctaed with touch, not light signalling. We studied gene expression in petioles during early canopy development when leaf hyponasty was visible but altered phytochrome signalling was not yet detectab...
ORGANISM(S): Arabidopsis thaliana 
2012-09-04 | E-GEOD-39010 | biostudies-arrayexpress
ProteomicsProteome changes of fibroblasts and endothelial cells upon incubation with human cytomegalovirus dense bodies
A mass spectrometry-based proteomics analysis was performed to study the proteome changes upon treatment with dense bodies derived from human cytomegalovirus infection.
ORGANISM(S): Homo sapiens (Human) 
2023-07-24 | PXD039032 | Pride
Hcmv Endothelial cells Dimethyl-labelling Dense bodies Fibroblasts 
ProteomicsApolipoprotein E is associated with dense deposits in dense deposit disease
C3 glomerulopathy (C3G) is a rare disease resulting from dysregulation of the alternative pathway (AP) of complement. C3G includes C3 glomerulonephritis (C3GN) and dense deposit disease (DDD). Both C3GN and DDD are characterized by bright glomerular C3 staining on immunofluorescence studies. However...
ORGANISM(S): Homo sapiens (Human) 
2024-10-22 | PXD045319 | Pride
Human Tandem mass spectrometry Kidney Lcm Glomeruli 
GenomicsTranscriptional profiling of dense and cystic organoids
Transcriptional profiling of dense and cystic organoids
PRJNA479819 | ENA
ProteomicsProximity labeling of dense core vesicle protein VMAT
Neuropeptide-containing dense core vesicles (DCVs) are generated in the neuronal cell body and circulate throughout the axonal arbor to supply distal release sites. This circulation depends on the anterograde kinesin-1 and kinesin-3 motors and the retrograde dynein-dynactin motor, however the adapto...
ORGANISM(S): Drosophila melanogaster (Fruit fly) 
2026-01-12 | PXD063200 | Pride
Synaptic vesicles Vmat Neurons Axonal transport Neuropeptide-containing dense core vesicles Drosophila 
GenomicsHOT regions are CpG dense promoters in C. elegans and humans
ChIP seq of Cfp-1 and H3K4me3 in C. elegans late embryos The coding region of F52B11.1a (cfp-1) was PCR amplified from N2 genomic DNA using Phusion polymerase (Finnzymes) and Gateway cloned into pDONR221. The cfp-1 coding region was then recombined into the MosSCI compatible vector pCFJ201 (which ...
ORGANISM(S): Caenorhabditis elegans 
2014-01-01 | E-GEOD-49870 | biostudies-arrayexpress
TranscriptomicsA Toxoplasma dense granule protein, GRA24, modulates the early immune response to infection by promoting a direct and sustained host p38 MAPK activation
Toxoplasma gondii, the causative agent of toxoplasmosis, is an obligate intracellular protozoan parasite that resides inside a parasitophorous vacuole. During infection, Toxoplasma actively remodels the transcriptome of its hosting cells with profound and coupled impact on the host immune response. ...
ORGANISM(S): Mus musculus 
2013-09-01 | E-GEOD-38782 | biostudies-arrayexpress
ProteomicsApical annuli are specialised sites of post-invasion secretion of dense granules in Toxoplasma
Toxoplasma gondii is an intracellular parasite that causes the disease toxoplasmosis in humans. It is a member of the phylum Apicomplexa that also includes significant human pathogens such as Plasmodium spp. and Cryptosporidium spp. causing malaria and diarrheal disease, respectively. These parasite...
ORGANISM(S): Toxoplasma gondii 
2024-01-25 | PXD044588 | Pride
Toxoplasma Exocytosis Secretion Lmbd Snare Apical annuli Dense granules 
TranscriptomicsGene expression profiles of pretreatment biopsies from dose-dense-docetaxel-treated breast cancers
The purpose of this study was to identify molecular markers of pathologic response to neoadjuvant dose-dense docetaxel treatment using gene expression profiling on pretreatment biopsies. Patients with high-risk, operable breast cancer were treated with 75 mg/m2 IV of docetaxel on day 1 of each cycl...
ORGANISM(S): Homo sapiens 
2011-04-22 | E-GEOD-28796 | biostudies-arrayexpress
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