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ProteomicsProteomic anlysis of dental calculus samples from Xiaohe
This analysis is a part of a larger study of the genomic origins of the Tarim Basin mummies. The dental calculus of seven individuals from Xiaohe contained ruminant dairy proteins, confirming milk consumption by the earliest inhabitants of Xiaohe.
ORGANISM(S): Homo sapiens (Human) 
2021-09-09 | PXD027706 | Pride
Lc-ms Dental calculus 
ProteomicsDirect evidence of milk consumption from ancient human dental calculus, UK
This study investigated the consumption of milk products in the archaeological record, utilizing human dental calculus as a reservoir of dietary proteins from archaeological samples from across Eurasia. Protein extraction and generation of tryptic peptides from dental calculus was performed using a ...
ORGANISM(S): Homo sapiens (Human) 
2015-02-26 | PXD001362 | Pride
Human Beta-lactoglobulin Dental calculus Dental plaque Lc-ms/ms 
ProteomicsMulti-omic detection of Mycobacterium leprae in archaeological human dental calculus
Mineralised dental plaque (calculus) has proven to be an excellent source of ancient biomolecules. In this study we present a Mycobacterium leprae genome (6.6-fold), the causative agent of leprosy, recovered via shotgun sequencing of 16th century human dental calculus from an individual from Trondhe...
ORGANISM(S): Homo sapiens (Human) 
2020-10-19 | PXD017836 | Pride
Dental calculus Palaeoproteomics 
ProteomicsDirect evidence of milk consumption from ancient human dental calculus, St Helena
This study investigated the consumption of milk products in the archaeological record, utilizing human dental calculus as a reservoir of dietary proteins from archaeological samples from across Eurasia. Protein extraction and generation of tryptic peptides from dental calculus was performed using a ...
ORGANISM(S): Homo sapiens (Human) 
2015-02-25 | PXD001357 | Pride
Human Beta-lactoglobulin Dental calculus Dental plaque Lc-ms/ms 
ProteomicsDirect evidence of milk consumption from ancient human dental calculus, northern Europe
This study investigated the consumption of milk products in the archaeological record, utilizing human dental calculus as a reservoir of dietary proteins from archaeological samples from across Eurasia. Protein extraction and generation of tryptic peptides from dental calculus was performed using a ...
ORGANISM(S): Homo sapiens (Human) 
2015-02-25 | PXD001361 | Pride
Human Beta-lactoglobulin Dental calculus Dental plaque Lc-ms/ms 
ProteomicsDirect evidence of milk consumption from ancient human dental calculus, northern southwest Asia
This study investigated the consumption of milk products in the archaeological record, utilizing human dental calculus as a reservoir of dietary proteins from archaeological samples from across Eurasia. Protein extraction and generation of tryptic peptides from dental calculus was performed using a ...
ORGANISM(S): Homo sapiens (Human) 
2015-02-26 | PXD001359 | Pride
Human Beta-lactoglobulin Dental calculus Dental plaque Lc-ms/ms 
ProteomicsPalmer et al: Dental Method Comparison
The dental calculus proteome from human remains is a considered a valuable archaeological resource for studying the diet, oral microbiome, health/disease of individuals and occupation activities individuals within past societies/civilisations. The combination of advancements in LC/MS instrument sens...
ORGANISM(S): Homo sapiens (Human) 
2021-02-19 | PXD023399 | Pride
Beta-lactoglobulin Orbi-trap Archaeologica dairy proteinl Edta Deamidation Mass spectrometry Qe Dental calculus proteome Sp3 Casein Hcl Acetone precipitation Ultrafiltration 
ProteomicsProtein Extraction from Ancient Teeth and Dental Calculus Compatible with Subsequent DNA Extraction
Dental calculus is becoming a crucial material in the study of past populations, with increasing interest in its proteomic and genomic content. Here we suggest further development of protocol for analysis of ancient proteins and a combined approach for subsequent ancient DNA extraction. We tested th...
ORGANISM(S): Homo sapiens (Human) 
2023-09-11 | PXD042668 | Pride
Protein extraction Palaeoproteomics Ancient dna Ancient proteins Dental calculus Bioarchaeology 
ProteomicsA unified protocol for simultaneous extraction of DNA and proteins from archaeological dental calculus
Archaeological materials are a finite resource, and efforts should be made to minimize destructive analyses. This can be achieved by using protocols combining extraction of several lines of evidence, which decreases the material needed for analyses while maximizing the information yield. Archaeologi...
ORGANISM(S): Homo sapiens (Human) 
2020-04-27 | PXD015817 | Pride
Ancient dna  palaeoproteomics  oral microbiome  dental plaque  metagenomics 
ProteomicsGenomic ancestry, diet and microbiomes of Upper Palaeolithic hunter-gatherers from San Teodoro cave (Sicily, Italy)
Recent improvements in the analysis ancient biomolecules from human remains and associated dental calculus have provided new insights into the prehistoric diet and past genetic diversity of our species. Here we present a “multi-omics” study, integrating genomic and proteomic analyses of two post-Las...
ORGANISM(S): Homo sapiens (Human) 
2022-10-27 | PXD024346 | Pride
Dental calculus Bone Human Sicily Italy Archaeology Lc-ms/ms 
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