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TranscriptomicsThe role of insulin resistance in experimental diabetic retinopathy - genetic and molecular aspects
Patients with long-duration diabetes develop cardiovascular complications resulting in highly increased mortality and complications which affect the kidneys, eyes and peripheral nerves associated with high morbidity. Among the diabetic complications, damage in the eye, diabetic retinopathy, is the m...
ORGANISM(S): Rattus norvegicus 
2017-03-31 | E-MTAB-5563 | biostudies-arrayexpress
ProteomicsSalivary biomarkers of diabetic retinopathy, part 1
To characterize human salivary proteome and determine changes in proteins expression in different stages of diabetic retinopathy.
ORGANISM(S): Homo sapiens (Human) 
2016-04-26 | PXD003723 | Pride
Human Type-2diabetes mellitus Saliva Diabetic retinopathy 
ProteomicsProteomics in exploring the endothelial dysfunction mechanism induced by serum exosomes from diabetic retinopathy and diabetic nephropathy patients
In this study, we used human glomerular endothelial cells (HGECs) as cells model, proteomics TMT-based LC-MS/MS was employed to discover the underlying mechanisms of endothelial dysfunction caused by SExos from diabetic retinopathy and nephropathy patients.
ORGANISM(S): Homo Sapiens 
2021-12-29 | PXD030660 |
ProteomicsSalivary biomarkers of diabetic retinopathy, part 3
To characterize the human salivary proteome and determine changes in proteins expression in different stages of diabetic retinopathy.
ORGANISM(S): Homo sapiens (Human) 
2016-04-26 | PXD003725 | Pride
Human Salivary proteome Retinopathy Type-2 diabetes mellitus 
UnknownRetinopathy During the First 5 Years of Type 1 Diabetes and Subsequent Risk of Advanced Retinopathy.
Not available
S-EPMC10090905 | biostudies-literature
ProteomicsAlterations in tear proteomes of adults with pre-diabetes and type 2 diabetes mellitus but without diabetic retinopathy
This study aims to explore the impact of type 2 diabetes mellitus (T2DM) on tear proteome, specifically investigating whether alterations occur before the development of diabetic retinopathy. Flush tear samples were collected from healthy subjects (n=13), subjects with preDM (n=16) and T2DM (n=18). ...
ORGANISM(S): Homo sapiens (Human) 
2025-08-04 | PXD062366 | Pride
Tear film  type 2 diabetes mellitus  mass spectrometry  proteomics Machine learning. 
UnknownRisk Factors for Retinopathy in Type 1 Diabetes: The DCCT/EDIC Study.
Not available
S-EPMC6489114 | biostudies-literature
ProteomicsExtracellular vesicles of human diabetic retinopathy retinal tissue and urine of diabetic retinopathy patients analyzed using mass spectrometry
Diabetic Retinopathy (DR) is a potentially blinding retinal disorder which develops through the pathogenesis of diabetes. Extracellular Vesicles (EVs) provide a novel biomarker for pre-symptomatic disease diagnosis and prognosis. Proteomic analysis was performed on explanted DR retinal tissue, DR r...
ORGANISM(S): Homo sapiens (Human) 
2022-12-31 | PXD034626 | Pride
Lc-ms/ms Exosome Diabetic retinopathy 
ProteomicsPutative tear fluid biomarkers of diabetic retinopathy
Identification of tear fluid biomarkers may offer a non-invasive strategy for detecting diabetic patients with increased risk of developing diabetic retinopathy (DR) or increased disease progression, thus helping both improving diagnostic accuracy and understanding the pathophysiology of the disease...
ORGANISM(S): Homo sapiens (Human) 
2022-05-31 | PXD033101 | Pride
Human Lc-msms Type 2 diabetes Proliferative diabetic retinopathy Nonproliferative diabetic retinopathy Tear fluid 
UnknownFactors associated with non-proliferative diabetic retinopathy in patients with type 1 and type 2 diabetes: the Japan Diabetes Complication and its Prevention prospective study (JDCP study 4).
Not available
S-EPMC6357241 | biostudies-literature
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