Sort   by:  
 Page size 
Histidyl dipeptides, such as carnosine, present in a micro-millimolar ranges in the heart, are synthesized via the enzyme carnosine synthase (Carns). These dipeptides facilitate glycolysis by proton buffering, form conjugates with reactive aldehydes, such as acrolein, and attenuate ischemia and repe...
ORGANISM(S): Mus <genus> 
2021-12-25 | PXD030647 |
Noncoding expansions of a hexanucleotide repeat (GGGGCC) in the C9orf72 gene are the most common cause of familial amyotrophic lateral sclerosis and frontotemporal dementia. Here we report transgenic mice carrying a bacterial artificial chromosome (BAC) containing the full human C9orf72 gene with ei...
ORGANISM(S): Mus musculus 
Integrated multilayer omics reveals the genomic, proteomic and metabolic influences of the histidyl dipeptides on heart
This study using a system biology approach of transcriptomics, proteomics and metabolomics, we elucidated the role of endogenous histidyl dipeptides on cellular pathways and myocardial metabolism. Our multi-omics approach for the first-time unravels the landscape of genetic, proteomic, and metabolic...
ORGANISM(S): Mus musculus 
2021-12-27 | GSE192583 | GEO
Global proteomics of Multiple Myeloma cell line MM.1S treated with pomalidomide or cyclic imide dipeptides for 10 h. The samples were labeled with TMT-16pro.
ORGANISM(S): Homo sapiens (Human) 
2022-07-28 | PXD025336 | Pride
Transcriptome-wide RNA binding analysis of C9orf72 poly(PR) dipeptides
Sort   by:  
 Page size