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ProteomicsDNAJC9 integrates heat shock molecular chaperones into the histone chaperone network
From biosynthesis to assembly into nucleosomes, histones are handed through a cascade of histone chaperones, which shield histones from non-specific interactions. Whether mechanisms exist to safeguard the histone fold during histone chaperone handover events or to release trapped intermediates is un...
ORGANISM(S): Homo sapiens (Human) 
2021-04-14 | PXD020268 | Pride
Hsp70 Histone chaperone Heat shock Hsp40 Dnajc9 Chaperone 
GenomicsDNAJC9 Integrates Heat Shock Molecular Chaperones into the Histone Chaperone Network
DNAJC9 Integrates Heat Shock Molecular Chaperones into the Histone Chaperone Network
PRJNA646272 | ENA
GenomicsDNAJC9 Integrates Heat Shock Molecular Chaperones into the Histone Chaperone Network
From biosynthesis to assembly into nucleosomes, histones are handed through a cascade of histone chaperones, which shield histones from non-specific interactions. Whether mechanisms exist to safeguard the histone fold during histone chaperone handover events or to release trapped intermediates is un...
ORGANISM(S): Homo sapiens 
2021-04-14 | GSE154445 | GEO
UnknownDNAJC9 integrates heat shock molecular chaperones into the histone chaperone network.
Not available
S-EPMC8221569 | biostudies-literature
GenomicsDNAJC9 prevents CENP-A mislocalization and chromosomal instability by maintaining the fidelity of H3-H4 supply chains
The centromeric histone H3 variant CENP-A is overexpressed in many cancers. Mislocalization of CENP-A to non-centromeric regions contributes to chromosomal instability (CIN), a hallmark of cancer. Despite these observations, pathways that promote and prevent CENP-A mislocalization remain poorly defi...
ORGANISM(S): Homo sapiens 
2024-03-26 | GSE253387 | GEO
ProteomicsDNAJC9 prevents CENP-A mislocalization and chromosomal instability by maintaining the fidelity of histone supply chains
The centromeric histone H3 variant CENP-A is overexpressed in many cancers. The mislocalization of CENP-A to noncentromeric regions contributes to chromosomal instability (CIN), a hallmark of cancer. However, pathways that promote or prevent CENP-A mislocalization remain poorly defined. Here, we per...
ORGANISM(S): Homo sapiens (Human) 
2024-04-11 | PXD043961 | Pride
Chromosomal instability Dnajc9 Epigenetics Mitosis Histone chaperone Centromere Chaf1b Caf-1 complex Cenp-a 
GenomicsDNAJC9 prevents CENP-A mislocalization and chromosomal instability by maintaining the fidelity of H3-H4 supply chains
DNAJC9 prevents CENP-A mislocalization and chromosomal instability by maintaining the fidelity of H3-H4 supply chains
PRJNA1065442 | ENA
UnknownDNAJC9 prevents CENP-A mislocalization and chromosomal instability by maintaining the fidelity of histone supply chains.
Not available
S-EPMC11148058 | biostudies-literature
UnknownThe ortholog of human DNAJC9 promotes histone H3-H4 degradation and is counteracted by Asf1 in fission yeast.
Not available
S-EPMC11775587 | biostudies-literature
UnknownDNAJC9 prevents CENP-A mislocalization and chromosomal instability by maintaining the fidelity of histone supply chains
Not available
S-SCDT-10_1038-S44318-024-00093-6 | biostudies-other
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