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MetabolomicsDried blood spots analysis for targeted and non-targeted exposomics

Dried blood spots (DBS) are an established sample type, widely used in newborn screening programs for monitoring metabolic diseases. Their minimally invasive nature offers great promise for assessing chemical exposures, particularly during early life stages and in large-scale epidemiological stud...

2025-10-09 | MTBLS13065 | MetaboLights
MetabolomicsComparing identified and statistically significant lipids and polar metabolites in 15-year old serum and dried blood spot samples for longitudinal studies
Not available
ORGANISM(S): Homo sapiens 
ST000608 | MetabolomicsWorkbench
MetabolomicsAn LC-MS untargeted metabolomic comparison between three blood microsampling devices, whole blood, and plasma

Blood microsampling (BµS) devices collect less than 100 µL of blood, offering a less invasive and more cost-effective alternative to venipuncture. However, its metabolomic comparability to conventional samples remains unclear, and standardized BµS metabolomic workflows are lacking. This study com...

2026-06-01 | MTBLS10740 | MetaboLights
MetabolomicsIntegrating Blood Microsampling Devices with CE-MS for Untargeted Analysis of Polar Metabolomics

Capillary electrophoresis–mass spectrometry (CE-MS) offers considerable advantages for polar compound metabolomics analysis, including simple workflows, fast method development, and suitability for small sample volumes. Blood microsampling (BμS) techniques (such as dried blood spots, quantitative...

2026-01-13 | MTBLS13090 | MetaboLights
MetabolomicsDeep insights into microsampling technologies for global lipidomic profiling of human whole blood using high-throughput LC-MS

In recent years, blood microsampling (BμS) technologies have gained popularity, as they offer simplicity, minimal invasiveness, and suitability for remote sample collection. In this study, the aim was to explore the potential of three BμS devices for reliable untargeted lipidomic profiling using ...

2025-09-30 | MTBLS10722 | MetaboLights
ProteomicsDIA proteomics of dried blood spot proteins by sodium carbonate
We developed a simple and sensitive analysis method for dried blood spot (DBS) proteins by sodium carbonate precipitation (SCP). We aimed to removing large amounts of hydrophilic blood proteins such as hemoglobin, albumin, fibrinogen and transferrin in DBS using a simple pretreatment with sodium car...
ORGANISM(S): Homo Sapiens (human) 
2020-01-20 | PXD017185 | JPOST Repository
GenomicsMicroRNA sequencing of BIBINS HIE dried blood spot
MicroRNA sequencing of BIBINS HIE dried blood spot
PRJNA750768 | ENA
ProteomicsHigh Field Asymmetric Waveform Ion Mobility Spectrometry in Non-targeted Bottom-up Proteomics of Dried Blood Spot
Dried Blood Spots samples are a rich source of proteins and have therefore great potential for proteomics biomarker discovery studies. Only a few articles have used DBS samples for non-targeted bottom-up protein analysis, probably due to the complexity of the DBS samples. Gas-phase separation by ion...
ORGANISM(S): Homo sapiens (Human) 
2018-05-03 | PXD007926 | Pride
Faims Dried blood spot Non-targeted Bottom-up Proteomics 
TranscriptomicsGene expression data from Guthrie blood-spot cards
Background: Standard Guthrie cards have been widely used to collect blood samples from neonates for newborn screening programs, and to a lesser extent, from normal controls and patients in research studies. Ease of blood collection (small quantity and less pain), transportation, and storage are the...
ORGANISM(S): Homo sapiens 
2012-12-07 | E-GEOD-19919 | biostudies-arrayexpress
ProteomicsComparative proteome analysis of the dried blood spot from children with autism spectrum disorder
Reliable biomarkers that assist in the diagnosis of autism spectrum disorder (ASD) are limited. This study aimed to identify proteins that can differentiate children with ASD from controls.
ORGANISM(S): Homo sapiens (Human) 
2025-09-17 | PXD063396 | Pride
Dried blood spot Comparative proteome Autism spectrum disorder 
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