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GenomicsCanine DUXC isoforms and functional similarity to human DUX4 [RNA-seq]
Canine DUXC isoforms and functional similarity to human DUX4 [RNA-seq]
PRJNA780789 | ENA
GenomicsCanine DUXC isoforms and functional similarity to human DUX4 [ChIP-seq]
Canine DUXC isoforms and functional similarity to human DUX4 [ChIP-seq]
PRJNA780790 | ENA
UnknownCanine DUXC: implications for DUX4 retrotransposition and preclinical models of FSHD.
Not available
S-EPMC9122657 | biostudies-literature
GenomicsCanine DUXC isoforms and functional similarity to human DUX4 [ChIP-seq]
Human DUX4 and mouse Dux transcription factors are normally expressed in the germ line and early embryonic cells where they activate the cleavage stage genes. The misexpression of DUX4 in skeletal muscles causes Facioscapulohumeral dystrophy (FSHD). In primates and rodents, DUX4 and Dux arose from r...
ORGANISM(S): Canis lupus familiaris 
2021-12-03 | GSE188926 | GEO
TranscriptomicsCanine DUXC isoforms and functional similarity to human DUX4 [RNA-seq]
Human DUX4 and mouse Dux transcription factors are normally expressed in the germ line and early embryonic cells where they activate the cleavage stage genes. The misexpression of DUX4 in skeletal muscles causes Facioscapulohumeral dystrophy (FSHD). In primates and rodents, DUX4 and Dux arose from r...
ORGANISM(S): Canis lupus familiaris 
2021-12-03 | GSE188927 | GEO
GenomicsPorcine DUXC and human DUX4 activate similar embryonic programs cross species: implications for preclinical model of FSHD
Porcine DUXC and human DUX4 activate similar embryonic programs cross species: implications for preclinical model of FSHD
PRJNA867402 | ENA
UnknownHuman DUX4 and porcine DUXC activate similar early embryonic programs in pig muscle cells: implications for preclinical models of FSHD.
Not available
S-EPMC10196675 | biostudies-literature
GenomicsCanine DUXC isoforms and functional similarity to human DUX4
Canine DUXC isoforms and functional similarity to human DUX4
PRJNA780786 | ENA
TranscriptomicsPorcine DUXC and human DUX4 activate similar embryonic programs cross species: implications for preclinical model of FSHD
DUX4 and its mouse ortholog Dux are normally expressed in the early embryo—the 4 cell or 2 cell cleavage stage embryo, respectively—and activate a portion of the first wave of zygotic gene expression. DUX4 is epigenetically suppressed in nearly all somatic tissue, whereas FSHD-causing mutations resu...
ORGANISM(S): Sus scrofa 
2023-05-10 | GSE210772 | GEO
ProteomicsLC-MS of FLAG-tagged C-terminal domain of human DUX4
DUX4 activates the first wave of zygotic gene expression in the early embryo. Mis-expression of DUX4 in skeletal muscle causes facioscapulohumeral dystrophy (FSHD), whereas expression in cancers suppresses IFNg-induction of MHC Class I and contributes to immune evasion. We show that the DUX4 protein...
ORGANISM(S): Homo sapiens (Human) 
2023-05-10 | PXD029215 | Pride
Interferon gamma Cgas Dux Interferon beta Rig-i Dux4 Mda5 Stat1 Duxc Interferon stimulated genes 
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