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ProteomicsDeep and fast label-free Dynamic Organellar Mapping - starvation + lysosomal pH block
The Dynamic Organellar Maps (DOMs) approach combines cell fractionation and shotgun-proteomics for global profiling analysis of protein subcellular localization. Here, we have drastically enhanced the performance of DOMs through data-independent acquisition (DIA) mass spectrometry (MS). DIA-DOMs ach...
ORGANISM(S): Homo sapiens (Human) 
2023-08-25 | PXD034969 | Pride
Bafilomycin a1 Dynamic organellar maps Dia Golgi proteins Starvation Data quality control Data-independent acquisition mass spectrometry Spatial proteomics Profiling analysis Endosomal transport 
ProteomicsDeep and fast label-free Dynamic Organellar Mapping - DIA datasets
The Dynamic Organellar Maps (DOMs) approach combines cell fractionation and shotgun-proteomics for global profiling analysis of protein subcellular localization. Here, we have drastically enhanced the performance of DOMs through data-independent acquisition (DIA) mass spectrometry (MS). DIA-DOMs ach...
ORGANISM(S): Homo sapiens (Human) 
2023-08-25 | PXD034971 | Pride
Dynamic organellar maps Dia Data quality control Data-independent acquisition mass spectrometry Spatial proteomics Profiling analysis 
ProteomicsDynamic Organellar Mapping in unperturbed yeast
Sophisticated techniques are available for systematic studies of yeast cell biology. However, it remains challenging to investigate protein subcellular localization changes on a proteome-wide scale. Here, we apply Dynamic Organellar Maps (DOMs) by label-free mass spectrometry to detect localization ...
ORGANISM(S): Saccharomyces cerevisiae Saccharomyces cerevisiae (Baker's yeast) 
2025-12-03 | PXD061762 | Pride
Dynamic organellar maps Yeast Subcellular localization 
ProteomicsDeep and fast label-free Dynamic Organellar Mapping - DDA data
The Dynamic Organellar Maps (DOMs) approach combines cell fractionation and shotgun-proteomics for global profiling analysis of protein subcellular localization. Here, we have drastically enhanced the performance of DOMs through data-independent acquisition (DIA) mass spectrometry (MS). DIA-DOMs ach...
ORGANISM(S): Homo sapiens (Human) 
2023-08-25 | PXD034962 | Pride
Dynamic organellar maps Dia Data quality control Data-independent acquisition mass spectrometry Spatial proteomics Profiling analysis 
ProteomicsAP-4 vesicles contribute to spatial control of autophagy via RUSC-dependent peripheral delivery of ATG9A
Adaptor protein 4 (AP-4) is an ancient membrane trafficking complex, whose function has largely remained elusive. In humans, AP-4 deficiency causes a severe neurological disorder of unknown aetiology. We apply unbiased proteomic methods, including ‘Dynamic Organellar Maps’, to find proteins whose su...
ORGANISM(S): Homo sapiens (Human) 
2018-09-27 | PXD010103 | Pride
Human cells Autophagy Dynamic organellar maps Ap-4 Vesicles 
ProteomicsDynamic Organellar Mapping in yeast exposed to ER stress
Sophisticated techniques are available for systematic studies of yeast cell biology. However, it remains challenging to investigate protein subcellular localization changes on a proteome-wide scale. Here, we apply Dynamic Organellar Maps (DOMs) by label-free mass spectrometry to detect localization ...
ORGANISM(S): Saccharomyces cerevisiae Saccharomyces cerevisiae (Baker's yeast) 
2025-12-03 | PXD061764 | Pride
Tunicamycin Dynamic organellar maps Yeast Er stress Dtt Subcellular localization 
UnknownDynamic Organellar Mapping in yeast reveals extensive protein localization changes during ER stress.
Not available
S-EPMC12672650 | biostudies-literature
UnknownDeep and fast label-free Dynamic Organellar Mapping.
Not available
S-EPMC10465578 | biostudies-literature
ProteomicsPattern Analysis of Organellar Maps for Interpretation of Pro-teomic Data
The human proton-coupled folate transporter (PCFT) was stably expressed as a fu-sion protein with a BioID2-HA in the C-terminal position (PCFT-BioID2). The uncom-plxed biotin transferase was used as a control to identify proteins that are biotinylated randomly due to sheer abundance and/or an unnatu...
ORGANISM(S): Homo sapiens (Human) 
2022-06-09 | PXD032297 | Pride
Proteomics  pattern analysis  bioinformatics  proximity labeling 
UnknownGlobal, quantitative and dynamic mapping of protein subcellular localization.
Not available
S-EPMC4959882 | biostudies-literature
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