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UnknownPaediatric cholestatic liver disease: Diagnosis, assessment of disease progression and mechanisms of fibrogenesis.
Not available
S-EPMC3097948 | biostudies-literature
TranscriptomicsStem cell lines of the early mouse embryo
Expression profiling of stem cell lines derived from the early embryo representing the trophoblast, primitive endoderm, early epiblast (inner cell mass E3.5) and late post-implantation epiblast (E5.5). Cells were grown without feeders and harvested. Comparisons were made to provide evidence of uniqu...
ORGANISM(S): Mus musculus 
2012-05-21 | E-GEOD-34799 | biostudies-arrayexpress
TranscriptomicsExpression and ChIP-seq analyses of embryonic stem cells, extraembryonic endoderm stem cells, and trophoblast stem cells
Bivalent histone domains have been proposed to contribute to pluripotency in embryonic stem cells, suggesting an epigenetic mechanism may regulate stem cell behavior in general. Here we compare histone modifications in two other stem cells derived from the blastocyst. We show that extraembryonic ste...
ORGANISM(S): Mus musculus 
2010-05-16 | E-GEOD-15519 | biostudies-arrayexpress
TranscriptomicsA Wnt-Bmp feedback circuit controls inter-tissue signaling dynamics in tooth organogenesis
Gene expression profiling of the epithelial and mesenchymal compartments of the developing mouse tooth using Laser Capture Microdissected (LCM) or enzymatic treatment with Dispase to isolate the dental epithelial and mesenchymal tissue, over a developmental period from E10.0-E14.5. The data is also ...
ORGANISM(S): Mus musculus 
2012-01-13 | E-GEOD-32321 | biostudies-arrayexpress
ProteomicsProteomics of Small Extracellular Vesicles from Melanoma DCC-Derived Cell Lines
Small extracellular vesicles (sEVs) were isolated from the culture supernatant of melanoma DCC-derived cell lines (MelDCC) after 48 hours of serum-free culture. sEVs were obtained through differential ultracentrifugation, specifically as the 100K pellet, following the protocol described in detail by...
ORGANISM(S): Homo sapiens (Human) 
2025-02-24 | PXD059510 | Pride
Lc-ms/ms Melanoma Extracellular vesicles 
TranscriptomicsGene Expression Profiles in Early Stages Uterine Serous Carcinomas in comparison to G3 and G1 Endometrioid Adenocarcinoma
The goal of this study was to identify differentially expressed genes (DEG) between uterine serouscarcinoma (USC) vs. early stages high/low grade endometrioid adenocarcinoma (EAC). Gene expression profiles of 33 cancer samples were analyzed (EAC-G1=11, EAC-G3=11, USC-G3=11) using the human genome wi...
ORGANISM(S): Homo sapiens 
2011-03-31 | E-GEOD-24537 | biostudies-arrayexpress
TranscriptomicsHigh titers and low fucosylation of early anti-SARS-CoV-2 IgG promote hyper-inflammation by anti-inflammatory macrophages (MIL10)
Patients diagnosed with coronavirus disease 2019 (COVID-19) mostly become critically ill around the time of activation of the adaptive immune response. Here, we provide evidence that antibodies play a role in the worsening of disease at the time of seroconversion. We show that early phase severe acu...
ORGANISM(S): Homo sapiens 
2021-04-30 | E-MTAB-10431 | biostudies-arrayexpress
ProteomicsDIA-MS to characterise lung cancer proteomic signature in blood plasma
DIA-MS plasma proteomics of a cohort of 490 lung cancer cases and 124 age-, sex-match controls collected post-diagnosis and pre-treatments. The cohort covers all stages, major histologies and smoking exposures and were recruited from Princess Margaret Cancer Centre’s Lung-CALIBRE program (Lung cance...
ORGANISM(S): Homo sapiens (Human) 
2026-10-26 | PXD072886 | Pride
Dia-ms Lung cancer Plasma Proteomics 
TranscriptomicsIn vitro antiplasmodial activity of Dicoma anomala subsp. gerrardii (Asteraceae): identification of its main active constituent and gene expression profiling.
To determine the transcriptional effects of a novel plant-based compound, dehydrobrachylaenolide, on P. falciparum, parasite cultures were treated with the compound over time. Samples were taken for analysis 2, 6, and 12 hours post-invasion of human red blood cells. Control cultures were treated sim...
ORGANISM(S): Plasmodium falciparum 3D7 
2011-11-01 | E-GEOD-29874 | biostudies-arrayexpress
UnknownThe early proximal αβ TCR signalosome specifies thymic selection outcome through a quantitative protein interaction network.
Not available
S-EPMC7252671 | biostudies-literature
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