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ProteomicsIdentification of ELOB interacting proteins by LC-MS/MS
To identify proteins that interact with ELOB (TCEB2) in mouse multiple tissues, including brain, fat, heart, intestine, liver, lung, ovary, spleen, stomach, testis, and uterus. Immunocoprecipitation (IP) experiments were performed and subjected to LC-MS/MS analysis and Label-free quantification.
ORGANISM(S): Mus musculus (Mouse) 
2026-02-13 | PXD064743 | Pride
Ip Elob Mouse Lc-ms/ms 
UnknownASB1 engages with ELOB to facilitate SQOR ubiquitination and H<sub>2</sub>S homeostasis during spermiogenesis.
Not available
S-EPMC11743861 | biostudies-literature
UnknownStructural analysis of viral infectivity factor of HIV type 1 and its interaction with A3G, EloC and EloB.
Not available
S-EPMC3935857 | biostudies-literature
TranscriptomicsPeptide-mediated inhibition of the transcriptional regulator Elongin BC induces apoptosis in cancer cells
Inhibition of protein-protein interactions (PPIs) via designed peptides is an effective strategy to perturb their biological functions. The Elongin BC heterodimer (ELOB/C) binds to a BC-box motif and is essential for cancer cell growth. Here, we report a peptide that mimics the high-affinity BC-box ...
ORGANISM(S): Homo sapiens 
2023-06-24 | GSE213767 | GEO
GenomicsElongin B orchestrates chromatin and transcriptional programs in H3K27M‑mutant diffuse midline glioma [XIII_ELOB_CUTandRUN]
Recurrent driver mutations in genes encoding histone H3 (H3.3K27M and H3.1K27M) are observed in ~80% of diffuse midline gliomas (DMG), which lead to aberrant gene regulation, yet the specific RNA polymerase 2 (Pol2) regulators inducing aberrant DMG transcription are not fully defined. We identified ...
ORGANISM(S): Homo sapiens 
2026-04-27 | GSE324878 | GEO
TranscriptomicsElongin B orchestrates chromatin and transcriptional programs in H3K27M‑mutant diffuse midline glioma [XIII_ELOBKO_RNAseq]
Recurrent driver mutations in genes encoding histone H3 (H3.3K27M and H3.1K27M) are observed in ~80% of diffuse midline gliomas (DMG), which lead to aberrant gene regulation, yet the specific RNA polymerase 2 (Pol2) regulators inducing aberrant DMG transcription are not fully defined. We identified ...
ORGANISM(S): Homo sapiens 
2026-04-27 | GSE324874 | GEO
GenomicsElongin B orchestrates chromatin and transcriptional programs in H3K27M‑mutant diffuse midline glioma [XIII_ELOBKO_chIP_ELOB_RNAPII]
Recurrent driver mutations in genes encoding histone H3 (H3.3K27M and H3.1K27M) are observed in ~80% of diffuse midline gliomas (DMG), which lead to aberrant gene regulation, yet the specific RNA polymerase 2 (Pol2) regulators inducing aberrant DMG transcription are not fully defined. We identified ...
ORGANISM(S): Homo sapiens 
2026-04-27 | GSE324875 | GEO
GenomicsElongin B orchestrates chromatin and transcriptional programs in H3K27M‑mutant diffuse midline glioma [XIII_K27MKO_CUTandRUN]
Recurrent driver mutations in genes encoding histone H3 (H3.3K27M and H3.1K27M) are observed in ~80% of diffuse midline gliomas (DMG), which lead to aberrant gene regulation, yet the specific RNA polymerase 2 (Pol2) regulators inducing aberrant DMG transcription are not fully defined. We identified ...
ORGANISM(S): Homo sapiens 
2026-04-27 | GSE324873 | GEO
ProteomicsARIH2 is a Vif-dependent regulator of CUL5-mediated APOBEC3G degradation in HIV infection: SRM-ELOB
SRM assays were generated for selected interactors of ELOB. SRM assay generation was performed using Skyline. For all targeted proteins, proteotypic peptides and optimal transitions for identification and quantification were selected based on the Skyline spectral library generated from the shotgun M...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) Human Immunodeficiency Virus 1 (ncbitaxon:11676) 
2020-02-17 | MSV000084962 | MassIVE
ProteomicsPeptide-mediated inhibition of the transcriptional regulator Elongin BC induces apoptosis in cancer cells
Inhibiting protein-protein interactions via designed peptides is a suitable strategy to block the function of important proteins in cells. The Elongin BC heterodimer (ELOB/C) is involved in transcription elongation and protein turnover. It interacts with target proteins via a so-called BC-box to mod...
ORGANISM(S): Homo sapiens (Human) 
2023-06-27 | PXD038414 | Pride
Peptide inhibition Elongin bc Cancer Prc2 Epop 
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