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The Polycomb group (PcG) and Trithorax group (TrxG) of proteins are required for stable and heritable maintenance of repressed and active gene expression states. Their antagonistic function on gene control, repression for PcG and activity for TrxG, is mediated by binding to chromatin and subsequent ...
ORGANISM(S): Drosophila melanogaster 
Despite significant progress in the mechanistic understanding of epigenetic reprogramming of cells, the basis of 'organ reprogramming' by (epi-)gene-environment interactions remained largely obscured. Here, we use the ether-induced haltere-to-wing transformations in Drosophila as a model for epigene...
ORGANISM(S): Drosophila melanogaster (Fruit fly) 
2024-04-24 | PXD050958 | Pride
Analysis of a clinical urothelial cancer cohort for their spatial tryptic peptide composition in two different tissue types, tumor and stroma, and two tumor subtypes, muscle-infiltrating and non muscle-infiltrating tumors.
ORGANISM(S): Homo sapiens (Human) 
2021-06-04 | PXD026459 | Pride
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