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Hox proteins have been proposed to act at multiple levels within regulatory hierarchies and to directly control the expression of a plethora of target genes. However, for any specific Hox protein or tissue, very few direct in vivo-regulated target genes have been identified. Here, we have identified...
ORGANISM(S): Drosophila melanogaster 
2006-11-23 | GSE6307 | GEO
The Hox genes are responsible for generating morphological diversity along the anterior-posterior axis during animal development. The Drosophila Hox gene Ultrabithorax (Ubx), for example, is required for specifying the identity of the third thoracic (T3) segment of the adult, which includes the dors...
ORGANISM(S): Drosophila melanogaster 
The UBX-regulated network in the haltere imaginal disc of D. melanogaster
The identity of every segment in the fruitfly Drosophila melanogaster is determined by the action of one or more homeotic selector genes. These genes encode proteins containing DNA-binding domains and function by regulating downstream target genes. The structure and function of homeotic genes are hi...
ORGANISM(S): Drosophila melanogaster 
Despite significant progress in the mechanistic understanding of epigenetic reprogramming of cells, the basis of 'organ reprogramming' by (epi-)gene-environment interactions remained largely obscured. Here, we use the ether-induced haltere-to-wing transformations in Drosophila as a model for epigene...
ORGANISM(S): Drosophila melanogaster (Fruit fly) 
2024-04-24 | PXD050958 | Pride
We investigated the transcriptional profile in Drosophila wing and haltere imaginal discs to identify differentialy expressed genes between the two tissues.
ORGANISM(S): Drosophila melanogaster 
2023-07-04 | GSE205352 | GEO
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