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ProteomicsShifted assembly and function of mSWI/SNF family subcomplexes underlie targetable dependencies in endometriod carcinomas
The mammalian SWI/SNF (mSWI/SNF) family of chromatin remodelers govern cell type-specific chromatin accessibility and gene expression and assemble as three distinct complexes: canonical BAF (cBAF), Polybromo-associated BAF (PBAF), and non-canonical BAF (ncBAF). ARID1A and ARID1B are paralog subunits...
ORGANISM(S): Homo sapiens (Human) 
2025-08-07 | PXD058236 | Pride
Voa1066 Dedifferentiated Cbaf Ncbaf Endometrical carcinoma Ucec Baf An3ca Endometriod carcinoma Pbaf 
GenomicsShifted assembly and function of mSWI/SNF family subcomplexes underlie targetable dependencies in endometriod carcinomas [ATAC/ChIP/RNA]
Shifted assembly and function of mSWI/SNF family subcomplexes underlie targetable dependencies in endometriod carcinomas [ATAC/ChIP/RNA]
PRJNA1195678 | ENA
GenomicsSingle Nucleus DNA Sequencing of Flow Sorted Archived Frozen and Formalin Fixed Paraffin Embedded Solid Tumors
We applied DNA content based flow cytometry methods to interrogate the genomes of clinical samples from 8 patients with ovarian cancer. These included 6 high grade serous ovarian carcinomas, a low grade serous carcinoma, and an endometriod carcinoma. Archived samples obtained from surgical resection...
ORGANISM(S): Homo sapiens 
2024-09-24 | GSE268921 | GEO
GenomicsMolecular stratification of endometrioid ovarian carcinoma predicts clinical outcome
Endometrioid ovarian carcinoma (EnOC) is an under-investigated type of ovarian carcinoma. Here, we report the largest genomic study of EnOCs to date, performing whole exome sequencing of 112 cases following rigorous pathological assessment. High frequencies of mutation were detected in CTNNB1(43%), ...
EGAS00001004366 | EGA
TranscriptomicsShifted assembly and function of mSWI/SNF family subcomplexes underlie targetable dependencies in endometriod carcinomas [ATAC/ChIP/RNA]
The mammalian SWI/SNF (mSWI/SNF) family of chromatin remodelers govern cell type-specific chromatin accessibility and gene expression and assemble as three distinct complexes: canonical BAF (cBAF), Polybromo-associated BAF (PBAF), and non-canonical BAF (ncBAF). ARID1A and ARID1B are paralog subunits...
ORGANISM(S): Homo sapiens 
2025-08-04 | GSE283800 | GEO
UnknownCCL25-CCR9 interaction modulates ovarian cancer cell migration, metalloproteinase expression, and invasion.
Not available
S-EPMC2927595 | biostudies-literature
UnknownPan-cancer analysis of TCGA data reveals notable signaling pathways.
Not available
S-EPMC4501083 | biostudies-literature
GenomicsSingle Nucleus DNA Sequencing of Flow Sorted Archived Frozen and Formalin Fixed Paraffin Embedded Solid Tumors
Single Nucleus DNA Sequencing of Flow Sorted Archived Frozen and Formalin Fixed Paraffin Embedded Solid Tumors
PRJNA1119467 | ENA
Genomicsada51201-2992-49f8-8298-f0d35db734ee - samples
Whole Exome sequencing data of tumour samples for 112 patients with endometrioid ovarian carcinoma in FASTQ format. Data was derived as summarized below: Library Preparation: Libraries were prepared from each DNA sample using the Illumina TruSeq Exome Library Prep kit (#FC-150-1002) according to th...
EGAD00001006389 | EGA
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